BDBM50073686 CHEMBL423029::[2-(5-tert-Butyl-1H-indol-3-yl)-ethyl]-dimethyl-amine
SMILES: CN(C)CCc1c[nH]c2ccc(cc12)C(C)(C)C
InChI Key: InChIKey=HDRWZHXQBFCRDG-UHFFFAOYSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 1D (Homo sapiens (Human)) | BDBM50073686 (CHEMBL423029 | [2-(5-tert-Butyl-1H-indol-3-yl)-eth...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 0.440 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description In vitro receptor binding affinity for cloned human 5-hydroxytryptamine 1D receptor | J Med Chem 42: 526-31 (1999) Article DOI: 10.1021/jm9805945 BindingDB Entry DOI: 10.7270/Q2668CBM | |||||||||||
More data for this Ligand-Target Pair |