BDBM50073833 (4-Benzyl-benzyl)-[2-((R)-2,2-dimethyl-1-methylcarbamoyl-propylcarbamoyl)-4-methyl-pentyl]-phosphinic acid::CHEMBL28170

SMILES: CNC(=O)[C@H](NC(=O)C(CC(C)C)CP(O)(=O)Cc1ccc(Cc2ccccc2)cc1)C(C)(C)C

InChI Key: InChIKey=KATBPZLMXQIZLF-BBMPLOMVSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50073833   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Collagenase 3 (Homo sapiens (Human))	BDBM50073833 ((4-Benzyl-benzyl)-[2-((R)-2,2-dimethyl-1-methylcar...) Show SMILES CNC(=O)[C@H](NC(=O)C(CC(C)C)CP(O)(=O)Cc1ccc(Cc2ccccc2)cc1)C(C)(C)C Show InChI InChI=1S/C28H41N2O4P/c1-20(2)16-24(26(31)30-25(27(32)29-6)28(3,4)5)19-35(33,34)18-23-14-12-22(13-15-23)17-21-10-8-7-9-11-21/h7-15,20,24-25H,16-19H2,1-6H3,(H,29,32)(H,30,31)(H,33,34)/t24?,25-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc Curated by ChEMBL					Assay Description Inhibition of recombinant Matrix metalloproteinase-13 (MMP-13)				Bioorg Med Chem Lett 9: 127-32 (1999) BindingDB Entry DOI: 10.7270/Q2JD4VZ4
					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM50073833 ((4-Benzyl-benzyl)-[2-((R)-2,2-dimethyl-1-methylcar...) Show SMILES CNC(=O)[C@H](NC(=O)C(CC(C)C)CP(O)(=O)Cc1ccc(Cc2ccccc2)cc1)C(C)(C)C Show InChI InChI=1S/C28H41N2O4P/c1-20(2)16-24(26(31)30-25(27(32)29-6)28(3,4)5)19-35(33,34)18-23-14-12-22(13-15-23)17-21-10-8-7-9-11-21/h7-15,20,24-25H,16-19H2,1-6H3,(H,29,32)(H,30,31)(H,33,34)/t24?,25-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc Curated by ChEMBL					Assay Description Inhibitory activity against recombinant matrix metalloprotease-1 (MMP-1).				Bioorg Med Chem Lett 9: 127-32 (1999) BindingDB Entry DOI: 10.7270/Q2JD4VZ4
					More data for this Ligand-Target Pair