BindingDB logo
myBDB logout

BDBM50073930 CHEMBL82963::{(S)-1-[(2,3-Dioxo-7-trifluoromethyl-1,2,3,4-tetrahydro-quinoxalin-5-ylmethyl)-amino]-ethyl}-phosphonic acid

SMILES: C[C@@H](NCc1cc(cc2[nH]c(=O)c(=O)[nH]c12)C(F)(F)F)P(O)(O)=O

InChI Key: InChIKey=RDTOXUOEIJUIMX-YFKPBYRVSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50073930   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glutamate receptor ionotropic, NMDA 1


(Homo sapiens (Human))		BDBM50073930
PNG
(CHEMBL82963 | {(S)-1-[(2,3-Dioxo-7-trifluoromethyl...)
Show SMILES C[C@@H](NCc1cc(cc2[nH]c(=O)c(=O)[nH]c12)C(F)(F)F)P(O)(O)=O
Show InChI InChI=1S/C12H13F3N3O5P/c1-5(24(21,22)23)16-4-6-2-7(12(13,14)15)3-8-9(6)18-11(20)10(19)17-8/h2-3,5,16H,4H2,1H3,(H,17,19)(H,18,20)(H2,21,22,23)/t5-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
PubMed
n/an/a 8n/an/an/an/an/an/a



University Hospital Zurich

Curated by ChEMBL


Assay Description
Compound was evaluated for its binding affinity for the glycine binding site on N-methyl-D-aspartate glutamate receptor by using [3H]-MDL-105,519 bin...

Bioorg Med Chem Lett 10: 75-8 (2000)


BindingDB Entry DOI: 10.7270/Q2M907WV
More data for this
Ligand-Target Pair