BDBM50074011 1'-[2-(1-naphthyl)ethyl]spiro[2,3-dihydro-1H-indene-2,4'-(hexahydropyridine)]-1-one::CHEMBL100052

SMILES: O=C1c2ccccc2CC11CCN(CCc2cccc3ccccc23)CC1

InChI Key: InChIKey=LXIPAAJKLDMQAA-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50074011   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50074011 (1'-[2-(1-naphthyl)ethyl]spiro[2,3-dihydro-1H-inden...) Show SMILES O=C1c2ccccc2CC11CCN(CCc2cccc3ccccc23)CC1 Show InChI InChI=1S/C25H25NO/c27-24-23-11-4-2-7-21(23)18-25(24)13-16-26(17-14-25)15-12-20-9-5-8-19-6-1-3-10-22(19)20/h1-11H,12-18H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	31	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co. Curated by ChEMBL					Assay Description Displacement of [125I]-HEAT from human Alpha-1C adrenergic receptor expressed in CHO cells				Bioorg Med Chem Lett 9: 291-4 (1999) BindingDB Entry DOI: 10.7270/Q20G3JBP
					More data for this Ligand-Target Pair
Adrenergic alpha1B (Homo sapiens (Human))	BDBM50074011 (1'-[2-(1-naphthyl)ethyl]spiro[2,3-dihydro-1H-inden...) Show SMILES O=C1c2ccccc2CC11CCN(CCc2cccc3ccccc23)CC1 Show InChI InChI=1S/C25H25NO/c27-24-23-11-4-2-7-21(23)18-25(24)13-16-26(17-14-25)15-12-20-9-5-8-19-6-1-3-10-22(19)20/h1-11H,12-18H2	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	49	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co. Curated by ChEMBL					Assay Description Displacement of [125I]-HEAT from human Alpha-1B adrenergic receptor expressed in LM cells				Bioorg Med Chem Lett 9: 291-4 (1999) BindingDB Entry DOI: 10.7270/Q20G3JBP
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Homo sapiens (Human))	BDBM50074011 (1'-[2-(1-naphthyl)ethyl]spiro[2,3-dihydro-1H-inden...) Show SMILES O=C1c2ccccc2CC11CCN(CCc2cccc3ccccc23)CC1 Show InChI InChI=1S/C25H25NO/c27-24-23-11-4-2-7-21(23)18-25(24)13-16-26(17-14-25)15-12-20-9-5-8-19-6-1-3-10-22(19)20/h1-11H,12-18H2	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	149	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co. Curated by ChEMBL					Assay Description Displacement of [125I]-HEAT from human Alpha-1D adrenergic receptor expressed in HEK cells				Bioorg Med Chem Lett 9: 291-4 (1999) BindingDB Entry DOI: 10.7270/Q20G3JBP
					More data for this Ligand-Target Pair