BDBM50074021 3-(4-Methoxy-benzenesulfonyl)-5-phenyl-pentanoic acid hydroxyamide::CHEMBL42521

SMILES: COc1ccc(cc1)S(=O)(=O)C(CCc1ccccc1)CC(=O)NO

InChI Key: InChIKey=FCCDGLDMUDUABZ-UHFFFAOYSA-N

Data: 6 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50074021   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50074021 (3-(4-Methoxy-benzenesulfonyl)-5-phenyl-pentanoic a...) Show SMILES COc1ccc(cc1)S(=O)(=O)C(CCc1ccccc1)CC(=O)NO Show InChI InChI=1S/C18H21NO5S/c1-24-15-8-11-16(12-9-15)25(22,23)17(13-18(20)19-21)10-7-14-5-3-2-4-6-14/h2-6,8-9,11-12,17,21H,7,10,13H2,1H3,(H,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Inhibition of matrix metalloproteinase-2 (MMP-2), gelatinase-A				J Med Chem 42: 541-4 (1999) Article DOI: 10.1021/jm980567e BindingDB Entry DOI: 10.7270/Q2VQ31VC
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50074021 (3-(4-Methoxy-benzenesulfonyl)-5-phenyl-pentanoic a...) Show SMILES COc1ccc(cc1)S(=O)(=O)C(CCc1ccccc1)CC(=O)NO Show InChI InChI=1S/C18H21NO5S/c1-24-15-8-11-16(12-9-15)25(22,23)17(13-18(20)19-21)10-7-14-5-3-2-4-6-14/h2-6,8-9,11-12,17,21H,7,10,13H2,1H3,(H,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	43	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Rhone Poulenc Rorer Curated by ChEMBL					Assay Description In vitro inhibition of human recombinant Matrix metalloproteinase-2.				Bioorg Med Chem Lett 10: 1637-40 (2000) BindingDB Entry DOI: 10.7270/Q20G3JDK
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50074021 (3-(4-Methoxy-benzenesulfonyl)-5-phenyl-pentanoic a...) Show SMILES COc1ccc(cc1)S(=O)(=O)C(CCc1ccccc1)CC(=O)NO Show InChI InChI=1S/C18H21NO5S/c1-24-15-8-11-16(12-9-15)25(22,23)17(13-18(20)19-21)10-7-14-5-3-2-4-6-14/h2-6,8-9,11-12,17,21H,7,10,13H2,1H3,(H,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Inhibition of matrix metalloproteinase-3 (MMP-3), stromelysin-1				J Med Chem 42: 541-4 (1999) Article DOI: 10.1021/jm980567e BindingDB Entry DOI: 10.7270/Q2VQ31VC
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50074021 (3-(4-Methoxy-benzenesulfonyl)-5-phenyl-pentanoic a...) Show SMILES COc1ccc(cc1)S(=O)(=O)C(CCc1ccccc1)CC(=O)NO Show InChI InChI=1S/C18H21NO5S/c1-24-15-8-11-16(12-9-15)25(22,23)17(13-18(20)19-21)10-7-14-5-3-2-4-6-14/h2-6,8-9,11-12,17,21H,7,10,13H2,1H3,(H,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	350	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Rhone Poulenc Rorer Curated by ChEMBL					Assay Description In vitro inhibition of human recombinant Matrix metalloproteinase-3.				Bioorg Med Chem Lett 10: 1637-40 (2000) BindingDB Entry DOI: 10.7270/Q20G3JDK
					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM50074021 (3-(4-Methoxy-benzenesulfonyl)-5-phenyl-pentanoic a...) Show SMILES COc1ccc(cc1)S(=O)(=O)C(CCc1ccccc1)CC(=O)NO Show InChI InChI=1S/C18H21NO5S/c1-24-15-8-11-16(12-9-15)25(22,23)17(13-18(20)19-21)10-7-14-5-3-2-4-6-14/h2-6,8-9,11-12,17,21H,7,10,13H2,1H3,(H,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	2.16E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Rhone Poulenc Rorer Curated by ChEMBL					Assay Description In vitro inhibition of human recombinant Matrix metalloproteinase-1.				Bioorg Med Chem Lett 10: 1637-40 (2000) BindingDB Entry DOI: 10.7270/Q20G3JDK
					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM50074021 (3-(4-Methoxy-benzenesulfonyl)-5-phenyl-pentanoic a...) Show SMILES COc1ccc(cc1)S(=O)(=O)C(CCc1ccccc1)CC(=O)NO Show InChI InChI=1S/C18H21NO5S/c1-24-15-8-11-16(12-9-15)25(22,23)17(13-18(20)19-21)10-7-14-5-3-2-4-6-14/h2-6,8-9,11-12,17,21H,7,10,13H2,1H3,(H,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Inhibition of matrix metalloproteinase-1 (MMP-1), fibroblast collagenase.				J Med Chem 42: 541-4 (1999) Article DOI: 10.1021/jm980567e BindingDB Entry DOI: 10.7270/Q2VQ31VC
					More data for this Ligand-Target Pair