null

SMILES: COc1ccc(cc1)S(=O)(=O)C(CC(=O)NO)Cc1ccccc1

InChI Key: InChIKey=AFJPLWPNTPTDED-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50074023   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50074023 (CHEMBL153469 | N-Hydroxy-3-(4-methoxy-benzenesulfo...) Show SMILES COc1ccc(cc1)S(=O)(=O)C(CC(=O)NO)Cc1ccccc1 Show InChI InChI=1S/C17H19NO5S/c1-23-14-7-9-15(10-8-14)24(21,22)16(12-17(19)18-20)11-13-5-3-2-4-6-13/h2-10,16,20H,11-12H2,1H3,(H,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Inhibition of matrix metalloproteinase-2 (MMP-2), gelatinase-A				J Med Chem 42: 541-4 (1999) Article DOI: 10.1021/jm980567e BindingDB Entry DOI: 10.7270/Q2VQ31VC
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50074023 (CHEMBL153469 | N-Hydroxy-3-(4-methoxy-benzenesulfo...) Show SMILES COc1ccc(cc1)S(=O)(=O)C(CC(=O)NO)Cc1ccccc1 Show InChI InChI=1S/C17H19NO5S/c1-23-14-7-9-15(10-8-14)24(21,22)16(12-17(19)18-20)11-13-5-3-2-4-6-13/h2-10,16,20H,11-12H2,1H3,(H,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Inhibition of matrix metalloproteinase-3 (MMP-3), stromelysin-1				J Med Chem 42: 541-4 (1999) Article DOI: 10.1021/jm980567e BindingDB Entry DOI: 10.7270/Q2VQ31VC
					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM50074023 (CHEMBL153469 | N-Hydroxy-3-(4-methoxy-benzenesulfo...) Show SMILES COc1ccc(cc1)S(=O)(=O)C(CC(=O)NO)Cc1ccccc1 Show InChI InChI=1S/C17H19NO5S/c1-23-14-7-9-15(10-8-14)24(21,22)16(12-17(19)18-20)11-13-5-3-2-4-6-13/h2-10,16,20H,11-12H2,1H3,(H,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Inhibition of matrix metalloproteinase-1 (MMP-1), fibroblast collagenase.				J Med Chem 42: 541-4 (1999) Article DOI: 10.1021/jm980567e BindingDB Entry DOI: 10.7270/Q2VQ31VC
					More data for this Ligand-Target Pair