BDBM50074052 1-(2-Benzyloxycarbonylamino-propionyl)-aziridine-2,3-dicarboxylic acid diethyl ester::CHEMBL2371130

SMILES: CCOC(=O)[C@@H]1[C@H](N1C(=O)[C@H](C)NC(=O)OCc1ccccc1)C(=O)OCC

InChI Key: InChIKey=XJWVZTXALMOTJD-FYXKPCITSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50074052   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Pro-cathepsin H (Homo sapiens (Human))	BDBM50074052 (1-(2-Benzyloxycarbonylamino-propionyl)-aziridine-2...) Show SMILES CCOC(=O)[C@@H]1[C@H](N1C(=O)[C@H](C)NC(=O)OCc1ccccc1)C(=O)OCC Show InChI InChI=1S/C19H24N2O7/c1-4-26-17(23)14-15(18(24)27-5-2)21(14)16(22)12(3)20-19(25)28-11-13-9-7-6-8-10-13/h6-10,12,14-15H,4-5,11H2,1-3H3,(H,20,25)/t12-,14?,15?,21?/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.60E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Albert-Ludwigs-University of Freiburg Curated by ChEMBL					Assay Description Inhibition constant for the non time dependent inhibition of Cathepsin H				J Med Chem 42: 560-72 (1999) Article DOI: 10.1021/jm981061z BindingDB Entry DOI: 10.7270/Q2M907TZ
					More data for this Ligand-Target Pair