BDBM50074318 5-(4-Bromo-phenyl)-1-(2,4-dichloro-phenyl)-4-methyl-1H-pyrazole-3-carboxylic acid cyclohexyl-methyl-amide::CHEMBL285473
SMILES: CN(C1CCCCC1)C(=O)c1nn(c(c1C)-c1ccc(Br)cc1)-c1ccc(Cl)cc1Cl
InChI Key: InChIKey=YGSUZSCDPGGGFY-UHFFFAOYSA-N
Data: 3 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cannabinoid receptor 1 (Rattus norvegicus (rat)) | BDBM50074318 (5-(4-Bromo-phenyl)-1-(2,4-dichloro-phenyl)-4-methy...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 56 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of South Carolina Curated by ChEMBL | Assay Description Inhibition of [3H]-CP-55,940 binding to cannabinoid receptor 1 in rat brain membranes. | J Med Chem 45: 1447-59 (2002) BindingDB Entry DOI: 10.7270/Q2222T3Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 1 (Rattus norvegicus (rat)) | BDBM50074318 (5-(4-Bromo-phenyl)-1-(2,4-dichloro-phenyl)-4-methy...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 76.7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Connecticut Curated by ChEMBL | Assay Description Binding affinity against Cannabinoid receptor 1 in rat forebrain | J Med Chem 42: 769-76 (1999) Article DOI: 10.1021/jm980363y BindingDB Entry DOI: 10.7270/Q2FJ2FZV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 2 (MOUSE) | BDBM50074318 (5-(4-Bromo-phenyl)-1-(2,4-dichloro-phenyl)-4-methy...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.26E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Connecticut Curated by ChEMBL | Assay Description Binding affinity against Cannabinoid receptor 2 in mouse spleen | J Med Chem 42: 769-76 (1999) Article DOI: 10.1021/jm980363y BindingDB Entry DOI: 10.7270/Q2FJ2FZV | |||||||||||
More data for this Ligand-Target Pair |