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BDBM50074477 CHEMBL168823::[9-(2-Bromo-4-isopropyl-phenyl)-2-methyl-9H-purin-6-yl]-dibutyl-amine

SMILES: CCCCN(CCCC)c1nc(C)nc2n(cnc12)-c1ccc(cc1Br)C(C)C

InChI Key: InChIKey=ZXULRPAUWYMCMT-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50074477   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Corticotropin releasing factor receptor 1


(Homo sapiens (Human))
BDBM50074477
PNG
(CHEMBL168823 | [9-(2-Bromo-4-isopropyl-phenyl)-2-m...)
Show SMILES CCCCN(CCCC)c1nc(C)nc2n(cnc12)-c1ccc(cc1Br)C(C)C
Show InChI InChI=1S/C23H32BrN5/c1-6-8-12-28(13-9-7-2)22-21-23(27-17(5)26-22)29(15-25-21)20-11-10-18(16(3)4)14-19(20)24/h10-11,14-16H,6-9,12-13H2,1-5H3
PDB
MMDB

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PC cid
PC sid
UniChem
Article
PubMed
6.10n/an/an/an/an/an/an/an/a



DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
Binding affinity to recombinant human Corticotropin releasing factor receptor 1 (hCRF1) expressed in 293EBNA cells


J Med Chem 42: 833-48 (1999)


Article DOI: 10.1021/jm980224g
BindingDB Entry DOI: 10.7270/Q2610ZGP
More data for this
Ligand-Target Pair