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SMILES: COCCN(CCOC)c1cc(C)nc2n(nnc12)-c1ccc(cc1Br)C(C)C

InChI Key: InChIKey=WFOBOXNCFPLGRG-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50074503   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Corticotropin-releasing factor receptor 1


(Homo sapiens (Human))		BDBM50074503
PNG
(CHEMBL169561 | [3-(2-Bromo-4-isopropyl-phenyl)-5-m...)
Show SMILES COCCN(CCOC)c1cc(C)nc2n(nnc12)-c1ccc(cc1Br)C(C)C
Show InChI InChI=1S/C21H28BrN5O2/c1-14(2)16-6-7-18(17(22)13-16)27-21-20(24-25-27)19(12-15(3)23-21)26(8-10-28-4)9-11-29-5/h6-7,12-14H,8-11H2,1-5H3
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Article
PubMed
 4.70n/an/an/an/an/an/an/an/a



DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
Binding affinity to recombinant human Corticotropin releasing factor receptor 1 (hCRF1) expressed in 293EBNA cells

J Med Chem 42: 833-48 (1999)


Article DOI: 10.1021/jm980224g
BindingDB Entry DOI: 10.7270/Q2610ZGP
More data for this
Ligand-Target Pair