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BDBM50074563 Bis-{4-[(1,3-Dioxo-1,3-dihydro-isoindol-2-ylmethoxyimino)-methyl]-1-propyl-pyridinium}dibromide::CHEMBL171664

SMILES: O=C1N(CO\N=C\c2cc[n+](CCCCCC[n+]3ccc(\C=N\OCN4C(=O)c5ccccc5C4=O)cc3)cc2)C(=O)c2ccccc12

InChI Key: InChIKey=SXJUIUPQBADZTJ-DNJOOXRZSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50074563   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cholinergic, muscarinic


(GUINEA PIG)		BDBM50074563
PNG
(Bis-{4-[(1,3-Dioxo-1,3-dihydro-isoindol-2-ylmethox...)
Show SMILES O=C1N(CO\N=C\c2cc[n+](CCCCCC[n+]3ccc(\C=N\OCN4C(=O)c5ccccc5C4=O)cc3)cc2)C(=O)c2ccccc12
Show InChI InChI=1S/C36H34N6O6/c43-33-29-9-3-4-10-30(29)34(44)41(33)25-47-37-23-27-13-19-39(20-14-27)17-7-1-2-8-18-40-21-15-28(16-22-40)24-38-48-26-42-35(45)31-11-5-6-12-32(31)36(42)46/h3-6,9-16,19-24H,1-2,7-8,17-18,25-26H2/q+2/b37-23+,38-24+
PDB

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/an/an/a 1.40E+3n/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Allosteric potency against the dissociation of radioligand [3H]-N-methylscopolamine from the porcine cardiac Muscarinic acetylcholine receptor M2

J Med Chem 42: 849-58 (1999)


Article DOI: 10.1021/jm981023f
BindingDB Entry DOI: 10.7270/Q22806RB
More data for this
Ligand-Target Pair