BindingDB logo
myBDB logout

BDBM50074566 2-{4-[4-(3-{1-[4-(1,3-dioxo-2,3-dihydro-1H-2-isoindolyl)butyl]-4-pyridiniumyl}propyl)-1-pyridiniumyl]butyl}-1,3-isoindolinedione; dibromide::CHEMBL354750

SMILES: O=C1N(CCCC[n+]2ccc(cc2)-c2cc[n+](CCCCN3C(=O)c4ccccc4C3=O)cc2)C(=O)c2ccccc12

InChI Key: InChIKey=XQAWVHUOJZHGEY-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50074566   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cholinergic, muscarinic


(GUINEA PIG)		BDBM50074566
PNG
(2-{4-[4-(3-{1-[4-(1,3-dioxo-2,3-dihydro-1H-2-isoin...)
Show SMILES O=C1N(CCCC[n+]2ccc(cc2)-c2cc[n+](CCCCN3C(=O)c4ccccc4C3=O)cc2)C(=O)c2ccccc12
Show InChI InChI=1S/C34H32N4O4/c39-31-27-9-1-2-10-28(27)32(40)37(31)19-7-5-17-35-21-13-25(14-22-35)26-15-23-36(24-16-26)18-6-8-20-38-33(41)29-11-3-4-12-30(29)34(38)42/h1-4,9-16,21-24H,5-8,17-20H2/q+2
PDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/an/an/a 4.65E+3n/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Allosteric potency against the dissociation of radioligand [3H]-N-methylscopolamine from the porcine cardiac Muscarinic acetylcholine receptor M2

J Med Chem 42: 849-58 (1999)


Article DOI: 10.1021/jm981023f
BindingDB Entry DOI: 10.7270/Q22806RB
More data for this
Ligand-Target Pair