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BDBM50074570 2-(4-{3-[1-(1,3-dioxo-2,3-dihydro-1H-2-isoindolylmethyl)-4-pyridiniumyl]propyl}-1-pyridiniumylmethyl)-1,3-isoindolinedione; dibromide::CHEMBL352356

SMILES: O=C1N(CC[n+]2ccc(CCCc3cc[n+](CCN4C(=O)c5ccccc5C4=O)cc3)cc2)C(=O)c2ccccc12

InChI Key: InChIKey=HLUKJECPCWDFDB-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50074570   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cholinergic, muscarinic


(GUINEA PIG)		BDBM50074570
PNG
(2-(4-{3-[1-(1,3-dioxo-2,3-dihydro-1H-2-isoindolylm...)
Show SMILES O=C1N(CC[n+]2ccc(CCCc3cc[n+](CCN4C(=O)c5ccccc5C4=O)cc3)cc2)C(=O)c2ccccc12
Show InChI InChI=1S/C33H30N4O4/c38-30-26-8-1-2-9-27(26)31(39)36(30)22-20-34-16-12-24(13-17-34)6-5-7-25-14-18-35(19-15-25)21-23-37-32(40)28-10-3-4-11-29(28)33(37)41/h1-4,8-19H,5-7,20-23H2/q+2
PDB

UniProtKB/SwissProt

B.MOAD
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AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 3.49E+3n/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Allosteric potency against the dissociation of radioligand [3H]-N-methylscopolamine from the porcine cardiac Muscarinic acetylcholine receptor M2

J Med Chem 42: 849-58 (1999)


Article DOI: 10.1021/jm981023f
BindingDB Entry DOI: 10.7270/Q22806RB
More data for this
Ligand-Target Pair