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BDBM50074571 Bis-{4-{[3-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-propoxyimino]-methyl}-1-methyl-pyridinium}propane; dibromide::CHEMBL169633

SMILES: O=C1N(CCCO\N=C\c2cc[n+](CCCCCC[n+]3ccc(\C=N\OCCCN4C(=O)c5ccccc5C4=O)cc3)cc2)C(=O)c2ccccc12

InChI Key: InChIKey=NNAHILHLKIFKHR-ZOZONKMWSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50074571   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cholinergic, muscarinic


(GUINEA PIG)		BDBM50074571
PNG
(Bis-{4-{[3-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-p...)
Show SMILES O=C1N(CCCO\N=C\c2cc[n+](CCCCCC[n+]3ccc(\C=N\OCCCN4C(=O)c5ccccc5C4=O)cc3)cc2)C(=O)c2ccccc12
Show InChI InChI=1S/C40H42N6O6/c47-37-33-11-3-4-12-34(33)38(48)45(37)21-9-27-51-41-29-31-15-23-43(24-16-31)19-7-1-2-8-20-44-25-17-32(18-26-44)30-42-52-28-10-22-46-39(49)35-13-5-6-14-36(35)40(46)50/h3-6,11-18,23-26,29-30H,1-2,7-10,19-22,27-28H2/q+2/b41-29+,42-30+
PDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/an/an/a 450n/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Allosteric potency against the dissociation of radioligand [3H]-N-methylscopolamine from the porcine cardiac Muscarinic acetylcholine receptor M2

J Med Chem 42: 849-58 (1999)


Article DOI: 10.1021/jm981023f
BindingDB Entry DOI: 10.7270/Q22806RB
More data for this
Ligand-Target Pair