Found 7 hits for monomerid = 50074745 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
PDGFR-beta/Platelet-derived growth factor receptor alpha
(Homo sapiens (Human)) | BDBM50074745
(3-(3-Chloro-phenyl)-5,7-dihydroxy-chromen-4-one | ...)Show InChI InChI=1S/C15H9ClO4/c16-9-3-1-2-8(4-9)11-7-20-13-6-10(17)5-12(18)14(13)15(11)19/h1-7,17-18H | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
NOVARTIS Limited
Curated by ChEMBL
| Assay Description Inhibition of Platelet-derived growth factor receptor-dependent phosphorylation |
J Med Chem 42: 1018-26 (1999)
Article DOI: 10.1021/jm980551o BindingDB Entry DOI: 10.7270/Q21835PV |
More data for this Ligand-Target Pair | |
Protein kinase C alpha type
(Homo sapiens (Human)) | BDBM50074745
(3-(3-Chloro-phenyl)-5,7-dihydroxy-chromen-4-one | ...)Show InChI InChI=1S/C15H9ClO4/c16-9-3-1-2-8(4-9)11-7-20-13-6-10(17)5-12(18)14(13)15(11)19/h1-7,17-18H | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
NOVARTIS Limited
Curated by ChEMBL
| Assay Description Inhibition of Protein kinase C alpha |
J Med Chem 42: 1018-26 (1999)
Article DOI: 10.1021/jm980551o BindingDB Entry DOI: 10.7270/Q21835PV |
More data for this Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50074745
(3-(3-Chloro-phenyl)-5,7-dihydroxy-chromen-4-one | ...)Show InChI InChI=1S/C15H9ClO4/c16-9-3-1-2-8(4-9)11-7-20-13-6-10(17)5-12(18)14(13)15(11)19/h1-7,17-18H | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 95 | n/a | n/a | n/a | n/a | n/a | n/a |
NOVARTIS Limited
Curated by ChEMBL
| Assay Description Inhibition of Epidermal growth factor receptor |
J Med Chem 42: 1018-26 (1999)
Article DOI: 10.1021/jm980551o BindingDB Entry DOI: 10.7270/Q21835PV |
More data for this Ligand-Target Pair | |
Epidermal growth factor receptor erbB1
(Mus musculus) | BDBM50074745
(3-(3-Chloro-phenyl)-5,7-dihydroxy-chromen-4-one | ...)Show InChI InChI=1S/C15H9ClO4/c16-9-3-1-2-8(4-9)11-7-20-13-6-10(17)5-12(18)14(13)15(11)19/h1-7,17-18H | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
NOVARTIS Limited
Curated by ChEMBL
| Assay Description Inhibition of EGF-dependent mouse keratinocyte MK cell proliferation |
J Med Chem 42: 1018-26 (1999)
Article DOI: 10.1021/jm980551o BindingDB Entry DOI: 10.7270/Q21835PV |
More data for this Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50074745
(3-(3-Chloro-phenyl)-5,7-dihydroxy-chromen-4-one | ...)Show InChI InChI=1S/C15H9ClO4/c16-9-3-1-2-8(4-9)11-7-20-13-6-10(17)5-12(18)14(13)15(11)19/h1-7,17-18H | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
NOVARTIS Limited
Curated by ChEMBL
| Assay Description Inhibition of p60 c-Src tyrosine kinase |
J Med Chem 42: 1018-26 (1999)
Article DOI: 10.1021/jm980551o BindingDB Entry DOI: 10.7270/Q21835PV |
More data for this Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50074745
(3-(3-Chloro-phenyl)-5,7-dihydroxy-chromen-4-one | ...)Show InChI InChI=1S/C15H9ClO4/c16-9-3-1-2-8(4-9)11-7-20-13-6-10(17)5-12(18)14(13)15(11)19/h1-7,17-18H | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
NOVARTIS Limited
Curated by ChEMBL
| Assay Description Inhibition of Epidermal growth factor receptor-dependent phosphorylation |
J Med Chem 42: 1018-26 (1999)
Article DOI: 10.1021/jm980551o BindingDB Entry DOI: 10.7270/Q21835PV |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase ABL
(Homo sapiens (Human)) | BDBM50074745
(3-(3-Chloro-phenyl)-5,7-dihydroxy-chromen-4-one | ...)Show InChI InChI=1S/C15H9ClO4/c16-9-3-1-2-8(4-9)11-7-20-13-6-10(17)5-12(18)14(13)15(11)19/h1-7,17-18H | PDB
KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
NOVARTIS Limited
Curated by ChEMBL
| Assay Description Inhibition of v-Abl tyrosine kinase |
J Med Chem 42: 1018-26 (1999)
Article DOI: 10.1021/jm980551o BindingDB Entry DOI: 10.7270/Q21835PV |
More data for this Ligand-Target Pair | |