BDBM50074805 3-Ethyl-2-phenyl-quinoline-4-carboxylic acid (1-phenyl-propyl)-amide::CHEMBL10134

SMILES: CCC(NC(=O)c1c(CC)c(nc2ccccc12)-c1ccccc1)c1ccccc1

InChI Key: InChIKey=RVDBXUCLTPUWIX-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50074805   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuromedin-K receptor (Homo sapiens (Human))	BDBM50074805 (3-Ethyl-2-phenyl-quinoline-4-carboxylic acid (1-ph...) Show SMILES CCC(NC(=O)c1c(CC)c(nc2ccccc12)-c1ccccc1)c1ccccc1 Show InChI InChI=1S/C27H26N2O/c1-3-21-25(27(30)29-23(4-2)19-13-7-5-8-14-19)22-17-11-12-18-24(22)28-26(21)20-15-9-6-10-16-20/h5-18,23H,3-4H2,1-2H3,(H,29,30)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	6.31	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northeast Ohio Medical University Curated by ChEMBL					Assay Description Binding affinity to human NK3 receptor expressed in CHO cells				Bioorg Med Chem Lett 21: 7405-11 (2011) Article DOI: 10.1016/j.bmcl.2011.10.014 BindingDB Entry DOI: 10.7270/Q2CC11Z5
					More data for this Ligand-Target Pair
Neuromedin-K receptor (Homo sapiens (Human))	BDBM50074805 (3-Ethyl-2-phenyl-quinoline-4-carboxylic acid (1-ph...) Show SMILES CCC(NC(=O)c1c(CC)c(nc2ccccc12)-c1ccccc1)c1ccccc1 Show InChI InChI=1S/C27H26N2O/c1-3-21-25(27(30)29-23(4-2)19-13-7-5-8-14-19)22-17-11-12-18-24(22)28-26(21)20-15-9-6-10-16-20/h5-18,23H,3-4H2,1-2H3,(H,29,30)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	7.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham S.p.A. Curated by ChEMBL					Assay Description Binding affinity towards cloned human Tachykinin receptor 3 (hNK-3) expressed in CHO cells using [125I][MePhe7]-NKB				J Med Chem 42: 1053-65 (1999) Article DOI: 10.1021/jm980633c BindingDB Entry DOI: 10.7270/Q2F47PTQ
					More data for this Ligand-Target Pair