null
SMILES: COc1ccc(cc1OC)-c1ccc(o1)-c1ccc(OC)c(OC)c1
InChI Key: InChIKey=ZESHRVUYCRWWFA-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Homo sapiens (Human)) | BDBM50074967 (2,5-Bis-(3,4-dimethoxy-phenyl)-furan | CHEMBL11093...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 560 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL | Assay Description PDE4A activity assessed using human recombinant purified GST-PDE4A248 | Bioorg Med Chem Lett 9: 323-6 (1999) BindingDB Entry DOI: 10.7270/Q27S7MXX | |||||||||||
More data for this Ligand-Target Pair |