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SMILES: COc1ccc(cc1OC1CCCC1)-c1ccc(o1)-c1ccc2ccccc2n1

InChI Key: InChIKey=PFZAQNOLLMZQSU-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50074968   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
cAMP-specific 3',5'-cyclic phosphodiesterase 4A


(Homo sapiens (Human))		BDBM50074968
PNG
(2-[5-(3-Cyclopentyloxy-4-methoxy-phenyl)-furan-2-y...)
Show SMILES COc1ccc(cc1OC1CCCC1)-c1ccc(o1)-c1ccc2ccccc2n1
Show InChI InChI=1S/C25H23NO3/c1-27-24-13-11-18(16-25(24)28-19-7-3-4-8-19)22-14-15-23(29-22)21-12-10-17-6-2-5-9-20(17)26-21/h2,5-6,9-16,19H,3-4,7-8H2,1H3
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PubMed
n/an/a 190n/an/an/an/an/an/a



Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL


Assay Description
PDE4A activity assessed using human recombinant purified GST-PDE4A248

Bioorg Med Chem Lett 9: 323-6 (1999)


BindingDB Entry DOI: 10.7270/Q27S7MXX
More data for this
Ligand-Target Pair