null
SMILES: CN(C(=O)CNC(=O)\C=C\C=C)c1ccc(Cl)c(COc2cccc3sc(C)nc23)c1Cl
InChI Key: InChIKey=RGYRXPGQPRYXCH-WEVVVXLNSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
B2 bradykinin receptor (Cavia porcellus) | BDBM50074991 ((E)-Penta-2,4-dienoic acid ({[2,4-dichloro-3-(2-me...) | MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 3.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Hoechst Marion Roussel GmbH Curated by ChEMBL | Assay Description Inhibition of BK-induced (4x10E-8M) contraction of isolated guinea pig ileum (GPI) | Bioorg Med Chem Lett 9: 327-32 (1999) BindingDB Entry DOI: 10.7270/Q2416W7C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
B2 bradykinin receptor (Cavia porcellus) | BDBM50074991 ((E)-Penta-2,4-dienoic acid ({[2,4-dichloro-3-(2-me...) | MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | n/a |
Hoechst Marion Roussel GmbH Curated by ChEMBL | Assay Description Inhibition of specific binding of [3H]-BK to bradykinin B2 receptors of guinea pig ileum (GPI) | Bioorg Med Chem Lett 9: 327-32 (1999) BindingDB Entry DOI: 10.7270/Q2416W7C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
B2 bradykinin receptor (Cavia porcellus) | BDBM50074991 ((E)-Penta-2,4-dienoic acid ({[2,4-dichloro-3-(2-me...) | MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 260 | n/a | n/a | n/a | n/a |
Hoechst Marion Roussel GmbH Curated by ChEMBL | Assay Description Inhibition of BK-induced (4x10E-8M) contraction of isolated guinea pig ileum (GPI) | Bioorg Med Chem Lett 9: 327-32 (1999) BindingDB Entry DOI: 10.7270/Q2416W7C | |||||||||||
More data for this Ligand-Target Pair |