BDBM50075003 5-Bromo-1-ethyl-3-[(4-fluoro-phenyl)-imidazol-1-yl-methyl]-1H-indole::CHEMBL111888

SMILES: CCn1cc(C(c2ccc(F)cc2)n2ccnc2)c2cc(Br)ccc12

InChI Key: InChIKey=LUWGVOJFHFMVCW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50075003   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aromatase (Homo sapiens (Human))	BDBM50075003 (5-Bromo-1-ethyl-3-[(4-fluoro-phenyl)-imidazol-1-yl...) Show SMILES CCn1cc(C(c2ccc(F)cc2)n2ccnc2)c2cc(Br)ccc12 Show InChI InChI=1S/C20H17BrFN3/c1-2-24-12-18(17-11-15(21)5-8-19(17)24)20(25-10-9-23-13-25)14-3-6-16(22)7-4-14/h3-13,20H,2H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
Nantes Curated by ChEMBL					Assay Description In vitro inhibition of human Cytochrome P450 19A1				Bioorg Med Chem Lett 9: 333-6 (1999) BindingDB Entry DOI: 10.7270/Q20C4TXZ
					More data for this Ligand-Target Pair