BDBM50075004 1-Ethyl-3-[(4-fluoro-phenyl)-imidazol-1-yl-methyl]-1H-indole::CHEMBL113637

SMILES: CCn1cc(C(c2ccc(F)cc2)n2ccnc2)c2ccccc12

InChI Key: InChIKey=RHABPMUKMVYRLG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50075004   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 19A1 (Homo sapiens (Human))	BDBM50075004 (1-Ethyl-3-[(4-fluoro-phenyl)-imidazol-1-yl-methyl]...) Show SMILES CCn1cc(C(c2ccc(F)cc2)n2ccnc2)c2ccccc12 Show InChI InChI=1S/C20H18FN3/c1-2-23-13-18(17-5-3-4-6-19(17)23)20(24-12-11-22-14-24)15-7-9-16(21)10-8-15/h3-14,20H,2H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	57	n/a	n/a	n/a	n/a	n/a	n/a
Nantes Curated by ChEMBL					Assay Description In vitro inhibition of human Cytochrome P450 19A1				Bioorg Med Chem Lett 9: 333-6 (1999) BindingDB Entry DOI: 10.7270/Q20C4TXZ
					More data for this Ligand-Target Pair