BDBM50075159 (E)-N-[(S)-1-(5-Methyl-4-oxo-4H-thieno[2,3-d][1,3]oxazin-2-yl)-ethyl]-3-quinolin-4-yl-acrylamide::CHEMBL137895

SMILES: C[C@H](NC(=O)\C=C\c1ccnc2ccccc12)c1nc2scc(C)c2c(=O)o1

InChI Key: InChIKey=OSOBYCAELZSMAY-GWJCSSMESA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50075159   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human herpesvirus 4 protease/capsid scaffold protein (Epstein-Barr virus (strain B95-8) (HHV-4) (Human h...)	BDBM50075159 ((E)-N-[(S)-1-(5-Methyl-4-oxo-4H-thieno[2,3-d][1,3]...) Show SMILES C[C@H](NC(=O)\C=C\c1ccnc2ccccc12)c1nc2scc(C)c2c(=O)o1 Show InChI InChI=1S/C21H17N3O3S/c1-12-11-28-20-18(12)21(26)27-19(24-20)13(2)23-17(25)8-7-14-9-10-22-16-6-4-3-5-15(14)16/h3-11,13H,1-2H3,(H,23,25)/b8-7+/t13-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Inhibitory activity against cytomegalovirus (CMV) protease was determined using quenched fluorescence assay				Bioorg Med Chem Lett 9: 443-8 (1999) BindingDB Entry DOI: 10.7270/Q2ZC822V
					More data for this Ligand-Target Pair
Human herpesvirus 2 protease (Human herpesvirus 2 (strain HG52) (HHV-2) (Human h...)	BDBM50075159 ((E)-N-[(S)-1-(5-Methyl-4-oxo-4H-thieno[2,3-d][1,3]...) Show SMILES C[C@H](NC(=O)\C=C\c1ccnc2ccccc12)c1nc2scc(C)c2c(=O)o1 Show InChI InChI=1S/C21H17N3O3S/c1-12-11-28-20-18(12)21(26)27-19(24-20)13(2)23-17(25)8-7-14-9-10-22-16-6-4-3-5-15(14)16/h3-11,13H,1-2H3,(H,23,25)/b8-7+/t13-/m0/s1	MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Inhibitory activity against herpes simplex virus type 2 (HSV-2) protease was determined using quenched fluorescence assay				Bioorg Med Chem Lett 9: 443-8 (1999) BindingDB Entry DOI: 10.7270/Q2ZC822V
					More data for this Ligand-Target Pair
Human herpesvirus 6 protease (Human herpesvirus 6A (strain Uganda-1102) (HHV-6 v...)	BDBM50075159 ((E)-N-[(S)-1-(5-Methyl-4-oxo-4H-thieno[2,3-d][1,3]...) Show SMILES C[C@H](NC(=O)\C=C\c1ccnc2ccccc12)c1nc2scc(C)c2c(=O)o1 Show InChI InChI=1S/C21H17N3O3S/c1-12-11-28-20-18(12)21(26)27-19(24-20)13(2)23-17(25)8-7-14-9-10-22-16-6-4-3-5-15(14)16/h3-11,13H,1-2H3,(H,23,25)/b8-7+/t13-/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Inhibitory activity against Varicella Zoster Virus (VZV) protease was determined using quenched fluorescence assay				Bioorg Med Chem Lett 9: 443-8 (1999) BindingDB Entry DOI: 10.7270/Q2ZC822V
					More data for this Ligand-Target Pair