BDBM50075169 (E)-3-(3-Chloro-phenyl)-N-[(S)-1-(5-methyl-4-oxo-4H-thieno[2,3-d][1,3]oxazin-2-yl)-ethyl]-acrylamide::CHEMBL423552

SMILES: C[C@H](NC(=O)\C=C\c1cccc(Cl)c1)c1nc2scc(C)c2c(=O)o1

InChI Key: InChIKey=XMZZUCYPEIYYRF-MLRMMBSGSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50075169   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human herpesvirus 2 protease (Human herpesvirus 2 (strain HG52) (HHV-2) (Human h...)	BDBM50075169 ((E)-3-(3-Chloro-phenyl)-N-[(S)-1-(5-methyl-4-oxo-4...) Show SMILES C[C@H](NC(=O)\C=C\c1cccc(Cl)c1)c1nc2scc(C)c2c(=O)o1 Show InChI InChI=1S/C18H15ClN2O3S/c1-10-9-25-17-15(10)18(23)24-16(21-17)11(2)20-14(22)7-6-12-4-3-5-13(19)8-12/h3-9,11H,1-2H3,(H,20,22)/b7-6+/t11-/m0/s1	MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	980	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Inhibitory activity against herpes simplex virus type 2 (HSV-2) protease was determined using quenched fluorescence assay				Bioorg Med Chem Lett 9: 443-8 (1999) BindingDB Entry DOI: 10.7270/Q2ZC822V
					More data for this Ligand-Target Pair
Human herpesvirus 6 protease (Human herpesvirus 6A (strain Uganda-1102) (HHV-6 v...)	BDBM50075169 ((E)-3-(3-Chloro-phenyl)-N-[(S)-1-(5-methyl-4-oxo-4...) Show SMILES C[C@H](NC(=O)\C=C\c1cccc(Cl)c1)c1nc2scc(C)c2c(=O)o1 Show InChI InChI=1S/C18H15ClN2O3S/c1-10-9-25-17-15(10)18(23)24-16(21-17)11(2)20-14(22)7-6-12-4-3-5-13(19)8-12/h3-9,11H,1-2H3,(H,20,22)/b7-6+/t11-/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Inhibitory activity against Varicella Zoster Virus (VZV) protease was determined using quenched fluorescence assay				Bioorg Med Chem Lett 9: 443-8 (1999) BindingDB Entry DOI: 10.7270/Q2ZC822V
					More data for this Ligand-Target Pair
Human herpesvirus 4 protease/capsid scaffold protein (Epstein-Barr virus (strain B95-8) (HHV-4) (Human h...)	BDBM50075169 ((E)-3-(3-Chloro-phenyl)-N-[(S)-1-(5-methyl-4-oxo-4...) Show SMILES C[C@H](NC(=O)\C=C\c1cccc(Cl)c1)c1nc2scc(C)c2c(=O)o1 Show InChI InChI=1S/C18H15ClN2O3S/c1-10-9-25-17-15(10)18(23)24-16(21-17)11(2)20-14(22)7-6-12-4-3-5-13(19)8-12/h3-9,11H,1-2H3,(H,20,22)/b7-6+/t11-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	960	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Inhibitory activity against cytomegalovirus (CMV) protease was determined using quenched fluorescence assay				Bioorg Med Chem Lett 9: 443-8 (1999) BindingDB Entry DOI: 10.7270/Q2ZC822V
					More data for this Ligand-Target Pair