null
SMILES: C[C@H](NC(=O)\C=C\C(=O)c1cccc(c1)C#N)c1nc2scc(C)c2c(=O)o1
InChI Key: InChIKey=AVOPNJYFZROGTB-SYTKJHMZSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Genome polyprotein (Human rhinovirus B) | BDBM50075177 ((E)-4-(3-Cyano-phenyl)-4-oxo-but-2-enoic acid [(S)...) | MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 410 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Inhibitory activity of the compound against varicella zoster virus (VZV) protease | Bioorg Med Chem Lett 9: 449-52 (1999) BindingDB Entry DOI: 10.7270/Q2TM799P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Capsid scaffolding protein (Human cytomegalovirus (strain AD169) (HHV-5) (Huma...) | BDBM50075177 ((E)-4-(3-Cyano-phenyl)-4-oxo-but-2-enoic acid [(S)...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 41 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Inhibitory activity against cytomegalovirus protease (CMV) | Bioorg Med Chem Lett 9: 449-52 (1999) BindingDB Entry DOI: 10.7270/Q2TM799P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Capsid scaffolding protein (Human herpesvirus 2 (strain HG52) (HHV-2) (Human h...) | BDBM50075177 ((E)-4-(3-Cyano-phenyl)-4-oxo-but-2-enoic acid [(S)...) | MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Inhibitory activity against herpes simplex virus protease (HSV-2) | Bioorg Med Chem Lett 9: 449-52 (1999) BindingDB Entry DOI: 10.7270/Q2TM799P | |||||||||||
More data for this Ligand-Target Pair |