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BDBM50075276 (R)-6-Amino-2-{(2R,3S)-3-(1H-indol-3-yl)-2-[2-oxo-3-(3-phenyl-butyl)-imidazolidin-1-yl]-butyrylamino}-hexanoic acid tert-butyl ester::CHEMBL147214

SMILES: CC(CCN1CCN([C@H]([C@@H](C)c2c[nH]c3ccccc23)C(=O)N[C@H](CCCCN)C(=O)OC(C)(C)C)C1=O)c1ccccc1

InChI Key: InChIKey=GFRYRGUIMFBXBH-LWUGRXNISA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50075276   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Somatostatin receptor type 2


(Homo sapiens (Human))		BDBM50075276
PNG
((R)-6-Amino-2-{(2R,3S)-3-(1H-indol-3-yl)-2-[2-oxo-...)
Show SMILES CC(CCN1CCN([C@H]([C@@H](C)c2c[nH]c3ccccc23)C(=O)N[C@H](CCCCN)C(=O)OC(C)(C)C)C1=O)c1ccccc1
Show InChI InChI=1S/C35H49N5O4/c1-24(26-13-7-6-8-14-26)18-20-39-21-22-40(34(39)43)31(25(2)28-23-37-29-16-10-9-15-27(28)29)32(41)38-30(17-11-12-19-36)33(42)44-35(3,4)5/h6-10,13-16,23-25,30-31,37H,11-12,17-22,36H2,1-5H3,(H,38,41)/t24?,25-,30+,31+/m0/s1
PDB

KEGG

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Similars
PubMed
 5.90n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity was evaluated against human Somatostatin receptor type 2 (hSSTR-2)

Bioorg Med Chem Lett 9: 491-6 (1999)


BindingDB Entry DOI: 10.7270/Q2FB5235
More data for this
Ligand-Target Pair