BDBM50075289 1-[5-amino-1-methyloxycarbonyl-(1R)-pentylcarbamoyl]-2-(1H-3-indolyl)-(1R)-ethyl spiro[2,3-dihydro-1H-indene-1,4'-(hexahydropyridine)]-1'-carboxylate::CHEMBL146022
SMILES: COC(=O)[C@@H](CCCCN)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)OC(=O)N1CCC2(CCc3ccccc23)CC1
InChI Key: InChIKey=RLJAGKCCDNSYPX-VSGBNLITSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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SSTR2 (MOUSE) | BDBM50075289 (1-[5-amino-1-methyloxycarbonyl-(1R)-pentylcarbamoy...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | 10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description In vitro binding affinity of the compound was evaluated against mouse Somatostatin receptor type 2 (mSSTR-2) | Bioorg Med Chem Lett 9: 491-6 (1999) BindingDB Entry DOI: 10.7270/Q2FB5235 | |||||||||||
More data for this Ligand-Target Pair |