BDBM50075721 (LVA)2-{2-[3-(4-Hydroxy-phenyl)-2-(methyl-phenylacetyl-amino)-propionylamino]-3-phenyl-propionylamino}-pentanedioic acid 5-amide 1-[(2-carbamoyl-1-{1-[2-(1-carbamoyl-4-guanidino-butylcarbamoyl)-pyrrolidine-1-carbonyl]-4-guanidino-butylcarbamoyl}-ethyl)-amide]::CHEMBL262035
SMILES: CN([C@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(N)=O)C(=O)Cc1ccccc1
InChI Key: InChIKey=ZENOFYULYVVPCE-VUGWUCEWSA-N
Data: 4 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Vasopressin V1a receptor (Homo sapiens (Human)) | BDBM50075721 ((LVA)2-{2-[3-(4-Hydroxy-phenyl)-2-(methyl-phenylac...) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.800 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
INSERM Curated by ChEMBL | Assay Description Displacement of [125I]- HO-LVA from human Vasopressin V1a receptor in membranes of CHO cells | J Med Chem 42: 1312-9 (1999) Article DOI: 10.1021/jm9804782 BindingDB Entry DOI: 10.7270/Q2057F3Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oxytocin receptor (Homo sapiens (Human)) | BDBM50075721 ((LVA)2-{2-[3-(4-Hydroxy-phenyl)-2-(methyl-phenylac...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
INSERM Curated by ChEMBL | Assay Description The inhibition constant (Ki(nM)) of the compound was determined by displacement of [125I]- HO-LVA radiolabeled ligand using membranes of CHO cells of... | J Med Chem 42: 1312-9 (1999) Article DOI: 10.1021/jm9804782 BindingDB Entry DOI: 10.7270/Q2057F3Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V1b receptor (Homo sapiens (Human)) | BDBM50075721 ((LVA)2-{2-[3-(4-Hydroxy-phenyl)-2-(methyl-phenylac...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 9.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
INSERM Curated by ChEMBL | Assay Description The inhibition constant (Ki(nM)) of the compound was determined by displacement of [125I]- HO-LVA radiolabeled ligand using membranes of CHO cells of... | J Med Chem 42: 1312-9 (1999) Article DOI: 10.1021/jm9804782 BindingDB Entry DOI: 10.7270/Q2057F3Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Homo sapiens (Human)) | BDBM50075721 ((LVA)2-{2-[3-(4-Hydroxy-phenyl)-2-(methyl-phenylac...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 282 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
INSERM Curated by ChEMBL | Assay Description The inhibition constant (Ki(nM)) of the compound was determined by displacement of [125I]- HO-LVA radiolabeled ligand using membranes of CHO cells of... | J Med Chem 42: 1312-9 (1999) Article DOI: 10.1021/jm9804782 BindingDB Entry DOI: 10.7270/Q2057F3Q | |||||||||||
More data for this Ligand-Target Pair |