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SMILES: CN1CCN(CC1)c1nc2ccccc2c-2c1CSc1ccccc-21

InChI Key: InChIKey=HTBGXIVKSXVHMI-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50076423   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
5-hydroxytryptamine receptor 3A/3B


(Rattus norvegicus-RAT)		BDBM50076423
PNG
(7-(4-Methyl-piperazin-1-yl)-6H-5-thia-8-aza-benzo[...)
Show SMILES CN1CCN(CC1)c1nc2ccccc2c-2c1CSc1ccccc-21
Show InChI InChI=1S/C21H21N3S/c1-23-10-12-24(13-11-23)21-17-14-25-19-9-5-3-7-16(19)20(17)15-6-2-4-8-18(15)22-21/h2-9H,10-14H2,1H3
PDB

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
 19n/an/an/an/an/an/an/an/a



Universit£ di Siena

Curated by ChEMBL


Assay Description
Inhibition of [3H]granisetron binding to 5-hydroxytryptamine 3 receptor of rat cortical membrane

J Med Chem 42: 1556-75 (1999)


Article DOI: 10.1021/jm981112s
BindingDB Entry DOI: 10.7270/Q2D50NPW
More data for this
Ligand-Target Pair