BDBM50076602 CHEMBL368772::[9-(2-Bromo-4-isopropyl-phenyl)-8-chloro-2-methyl-9H-purin-6-yl]-butyl-ethyl-amine
SMILES: CCCCN(CC)c1nc(C)nc2n(c(Cl)nc12)-c1ccc(cc1Br)C(C)C
InChI Key: InChIKey=WTKAAUXEWBUKHL-UHFFFAOYSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human)) | BDBM50076602 (CHEMBL368772 | [9-(2-Bromo-4-isopropyl-phenyl)-8-c...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
DuPont Pharmaceuticals Company Curated by ChEMBL | Assay Description Binding affinity for transfected human Corticotropin releasing factor receptor expressed in HEK 293E cells using [125I]-TYR-oCRH as the displaced rad... | Bioorg Med Chem Lett 9: 967-72 (1999) BindingDB Entry DOI: 10.7270/Q26H4GKK | |||||||||||
More data for this Ligand-Target Pair |