BDBM50076694 5-Pentafluoroethyl-4-trifluoromethyl-5,6,7,8-tetrahydro-1-oxa-8-aza-anthracen-2-one::CHEMBL266928

SMILES: FC(F)(F)c1cc(=O)oc2cc3NCCC(c3cc12)C(F)(F)C(F)(F)F

InChI Key: InChIKey=YRBHIOJIJNNVRF-UHFFFAOYSA-N

Data: 2 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50076694   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Androgen receptor (Homo sapiens (Human))	BDBM50076694 (5-Pentafluoroethyl-4-trifluoromethyl-5,6,7,8-tetra...) Show SMILES FC(F)(F)c1cc(=O)oc2cc3NCCC(c3cc12)C(F)(F)C(F)(F)F Show InChI InChI=1S/C15H9F8NO2/c16-13(17,15(21,22)23)8-1-2-24-10-5-11-7(3-6(8)10)9(14(18,19)20)4-12(25)26-11/h3-5,8,24H,1-2H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	13	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description In vitro agonistic activity against human androgen receptor using cotransfection assay in CV-1 cells.				Bioorg Med Chem Lett 9: 1003-8 (1999) BindingDB Entry DOI: 10.7270/Q2JS9PM8
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50076694 (5-Pentafluoroethyl-4-trifluoromethyl-5,6,7,8-tetra...) Show SMILES FC(F)(F)c1cc(=O)oc2cc3NCCC(c3cc12)C(F)(F)C(F)(F)F Show InChI InChI=1S/C15H9F8NO2/c16-13(17,15(21,22)23)8-1-2-24-10-5-11-7(3-6(8)10)9(14(18,19)20)4-12(25)26-11/h3-5,8,24H,1-2H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description In vitro agonistic activity against human androgen receptor using cotransfection assay in CV-1 cells.				Bioorg Med Chem Lett 9: 1003-8 (1999) BindingDB Entry DOI: 10.7270/Q2JS9PM8
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50076694 (5-Pentafluoroethyl-4-trifluoromethyl-5,6,7,8-tetra...) Show SMILES FC(F)(F)c1cc(=O)oc2cc3NCCC(c3cc12)C(F)(F)C(F)(F)F Show InChI InChI=1S/C15H9F8NO2/c16-13(17,15(21,22)23)8-1-2-24-10-5-11-7(3-6(8)10)9(14(18,19)20)4-12(25)26-11/h3-5,8,24H,1-2H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>10	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description In vitro binding affinity at human androgen receptor transfected into COS cells.				Bioorg Med Chem Lett 9: 1003-8 (1999) BindingDB Entry DOI: 10.7270/Q2JS9PM8
					More data for this Ligand-Target Pair