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SMILES: CCN(c1nc(C)cc(n1)-c1ccccc1C(F)(F)F)c1ccc(cc1Br)C(C)=O

InChI Key: InChIKey=UNYKCLXPBPYASU-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50076746   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Corticotropin-releasing factor receptor 1


(Homo sapiens (Human))		BDBM50076746
PNG
(1-(3-Bromo-4-{ethyl-[4-methyl-6-(2-trifluoromethyl...)
Show SMILES CCN(c1nc(C)cc(n1)-c1ccccc1C(F)(F)F)c1ccc(cc1Br)C(C)=O
Show InChI InChI=1S/C22H19BrF3N3O/c1-4-29(20-10-9-15(14(3)30)12-18(20)23)21-27-13(2)11-19(28-21)16-7-5-6-8-17(16)22(24,25)26/h5-12H,4H2,1-3H3
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PubMed
 4.60n/an/an/an/an/an/an/an/a



DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
Displacement of [125I]-TYR-ovine CRH from cloned human corticotropin releasing factor receptor 1 expressed in 293 EBNA cells

Bioorg Med Chem Lett 9: 1057-62 (1999)


BindingDB Entry DOI: 10.7270/Q25M64WZ
More data for this
Ligand-Target Pair