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SMILES: CCN(c1nc(C)cc(n1)-c1ccccc1C(F)(F)F)c1ccc(cc1Br)C(C)C

InChI Key: InChIKey=ICJLTUMDXNLFPV-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50076754   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Corticotropin-releasing factor receptor 1


(Homo sapiens (Human))		BDBM50076754
PNG
((2-Bromo-4-isopropyl-phenyl)-ethyl-[4-methyl-6-(2-...)
Show SMILES CCN(c1nc(C)cc(n1)-c1ccccc1C(F)(F)F)c1ccc(cc1Br)C(C)C
Show InChI InChI=1S/C23H23BrF3N3/c1-5-30(21-11-10-16(14(2)3)13-19(21)24)22-28-15(4)12-20(29-22)17-8-6-7-9-18(17)23(25,26)27/h6-14H,5H2,1-4H3
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PubMed
 3.10n/an/an/an/an/an/an/an/a



DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
Displacement of [125I]-TYR-ovine CRH from cloned human corticotropin releasing factor receptor 1 expressed in 293 EBNA cells

Bioorg Med Chem Lett 9: 1057-62 (1999)


BindingDB Entry DOI: 10.7270/Q25M64WZ
More data for this
Ligand-Target Pair