BDBM50076764 (2-Bromo-4-methylsulfanyl-phenyl)-ethyl-[4-methyl-6-(2-trifluoromethyl-phenyl)-pyrimidin-2-yl]-amine::CHEMBL274578

SMILES: CCN(c1nc(C)cc(n1)-c1ccccc1C(F)(F)F)c1ccc(SC)cc1Br

InChI Key: InChIKey=MRHWSPVXCVPEJL-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50076764   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50076764 ((2-Bromo-4-methylsulfanyl-phenyl)-ethyl-[4-methyl-...) Show SMILES CCN(c1nc(C)cc(n1)-c1ccccc1C(F)(F)F)c1ccc(SC)cc1Br Show InChI InChI=1S/C21H19BrF3N3S/c1-4-28(19-10-9-14(29-3)12-17(19)22)20-26-13(2)11-18(27-20)15-7-5-6-8-16(15)21(23,24)25/h5-12H,4H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Displacement of [125I]-TYR-ovine CRH from cloned human corticotropin releasing factor receptor 1 expressed in 293 EBNA cells				Bioorg Med Chem Lett 9: 1057-62 (1999) BindingDB Entry DOI: 10.7270/Q25M64WZ
					More data for this Ligand-Target Pair