BindingDB logo
myBDB logout

null

SMILES: CCN(c1nc(C)cc(n1)-c1ccccc1C(F)(F)F)c1ccc(Br)cc1Br

InChI Key: InChIKey=YOJGNPZDDWDWMA-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50076768   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Corticotropin-releasing factor receptor 1


(Homo sapiens (Human))		BDBM50076768
PNG
((2,4-Dibromo-phenyl)-ethyl-[4-methyl-6-(2-trifluor...)
Show SMILES CCN(c1nc(C)cc(n1)-c1ccccc1C(F)(F)F)c1ccc(Br)cc1Br
Show InChI InChI=1S/C20H16Br2F3N3/c1-3-28(18-9-8-13(21)11-16(18)22)19-26-12(2)10-17(27-19)14-6-4-5-7-15(14)20(23,24)25/h4-11H,3H2,1-2H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
PubMed
 5.80n/an/an/an/an/an/an/an/a



DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
Displacement of [125I]-TYR-ovine CRH from cloned human corticotropin releasing factor receptor 1 expressed in 293 EBNA cells

Bioorg Med Chem Lett 9: 1057-62 (1999)


BindingDB Entry DOI: 10.7270/Q25M64WZ
More data for this
Ligand-Target Pair