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SMILES: CC(C)[C@@H](N(C)S(=O)(=O)c1ccc(cc1)-c1nnn(n1)-c1ccccc1)C(O)=O

InChI Key: InChIKey=GEHDRTPNVZSFGI-QGZVFWFLSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50077160   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Matrix metalloproteinase-9


(Homo sapiens (Human))		BDBM50077160
PNG
((R)-3-Methyl-2-{methyl-[4-(2-phenyl-2H-tetrazol-5-...)
Show SMILES CC(C)[C@@H](N(C)S(=O)(=O)c1ccc(cc1)-c1nnn(n1)-c1ccccc1)C(O)=O
Show InChI InChI=1S/C19H21N5O4S/c1-13(2)17(19(25)26)23(3)29(27,28)16-11-9-14(10-12-16)18-20-22-24(21-18)15-7-5-4-6-8-15/h4-13,17H,1-3H3,(H,25,26)/t17-/m1/s1
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MMDB

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Article
PubMed
n/an/a 870n/an/an/an/an/an/a



Shionogi & Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory activity against Matrix metalloproteinase-9 (concentration required for 50% inhibition of enzyme activity)

J Med Chem 42: 1723-38 (1999)


Article DOI: 10.1021/jm980514x
BindingDB Entry DOI: 10.7270/Q2KP81BQ
More data for this
Ligand-Target Pair