null
SMILES: Brc1cccc(Nc2ncnc3ccc(NC(=O)C=C)nc23)c1
InChI Key: InChIKey=AUDDREUYBAHNSP-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM50077230 (CHEMBL296168 | N-[4-(3-Bromo-phenylamino)-pyrido[3...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 5.60 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Auckland Curated by ChEMBL | Assay Description Inhibition of EGF-stimulated autophosphorylation of epidermal growth factor receptor (EGFR) in A431 cells | J Med Chem 42: 1803-15 (1999) Article DOI: 10.1021/jm9806603 BindingDB Entry DOI: 10.7270/Q2B56HZG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM50077230 (CHEMBL296168 | N-[4-(3-Bromo-phenylamino)-pyrido[3...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Auckland Curated by ChEMBL | Assay Description Inhibition of phosphorylation of glutamic acid/tyrosine random copolymer by isolated epidermal growth factor receptor (EGFR) | J Med Chem 42: 1803-15 (1999) Article DOI: 10.1021/jm9806603 BindingDB Entry DOI: 10.7270/Q2B56HZG | |||||||||||
More data for this Ligand-Target Pair |