null

SMILES: C(CCc1ccccc1)CNCCOc1cccc2[nH]ccc12

InChI Key: InChIKey=XLIMGWVIUMZMMX-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50077588   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50077588 (CHEMBL59737 | [2-(1H-Indol-4-yloxy)-ethyl]-(4-phen...) Show SMILES C(CCc1ccccc1)CNCCOc1cccc2[nH]ccc12 Show InChI InChI=1S/C20H24N2O/c1-2-7-17(8-3-1)9-4-5-13-21-15-16-23-20-11-6-10-19-18(20)12-14-22-19/h1-3,6-8,10-12,14,21-22H,4-5,9,13,15-16H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity towards 5-hydroxytryptamine 1A receptor by the displacement of [3H]-8-OH-DPAT radioligand in rat hippocampal homogenates				J Med Chem 42: 2007-20 (1999) Article DOI: 10.1021/jm990023s BindingDB Entry DOI: 10.7270/Q25D8R1W
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50077588 (CHEMBL59737 | [2-(1H-Indol-4-yloxy)-ethyl]-(4-phen...) Show SMILES C(CCc1ccccc1)CNCCOc1cccc2[nH]ccc12 Show InChI InChI=1S/C20H24N2O/c1-2-7-17(8-3-1)9-4-5-13-21-15-16-23-20-11-6-10-19-18(20)12-14-22-19/h1-3,6-8,10-12,14,21-22H,4-5,9,13,15-16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	5.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Laboratories Curated by ChEMBL					Assay Description In vitro high binding affinity towards Dopamine receptor D2 by the displacement of [3H]-quinpirole radioligand in rat striatal membranes				J Med Chem 42: 2007-20 (1999) Article DOI: 10.1021/jm990023s BindingDB Entry DOI: 10.7270/Q25D8R1W
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50077588 (CHEMBL59737 | [2-(1H-Indol-4-yloxy)-ethyl]-(4-phen...) Show SMILES C(CCc1ccccc1)CNCCOc1cccc2[nH]ccc12 Show InChI InChI=1S/C20H24N2O/c1-2-7-17(8-3-1)9-4-5-13-21-15-16-23-20-11-6-10-19-18(20)12-14-22-19/h1-3,6-8,10-12,14,21-22H,4-5,9,13,15-16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Laboratories Curated by ChEMBL					Assay Description In vitro low binding affinity towards Dopamine receptor D2 by the displacement of [3H]-spiperone radioligand in rat striatal membranes				J Med Chem 42: 2007-20 (1999) Article DOI: 10.1021/jm990023s BindingDB Entry DOI: 10.7270/Q25D8R1W
					More data for this Ligand-Target Pair