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BDBM50077948 CHEMBL3417121

SMILES: CC(C)[C@@]1(CC[C@H](C1)NC1CCc2ccc(C)cc12)C(=O)N1CCc2ccc(cc2C1)C(F)(F)F

InChI Key: InChIKey=JOGCMTOEJFSKKV-VTBJCVEASA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50077948   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
C-C chemokine receptor type 2


(Homo sapiens (Human))		BDBM50077948
PNG
(CHEMBL3417121)
Show SMILES CC(C)[C@@]1(CC[C@H](C1)NC1CCc2ccc(C)cc12)C(=O)N1CCc2ccc(cc2C1)C(F)(F)F |r|
Show InChI InChI=1S/C29H35F3N2O/c1-18(2)28(12-10-24(16-28)33-26-9-7-21-5-4-19(3)14-25(21)26)27(35)34-13-11-20-6-8-23(29(30,31)32)15-22(20)17-34/h4-6,8,14-15,18,24,26,33H,7,9-13,16-17H2,1-3H3/t24-,26?,28+/m1/s1
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Article
PubMed
 23n/an/an/an/an/an/an/an/a



Leiden University

Curated by ChEMBL


Assay Description
Displacement of 0.1 nM [125I]CCL2 from human CCR2 expressing human U2OS cell membrane by scintillation spectrometry

Eur J Med Chem 93: 121-34 (2015)


Article DOI: 10.1016/j.ejmech.2015.01.063
BindingDB Entry DOI: 10.7270/Q25M67DX
More data for this
Ligand-Target Pair