BDBM50078082 5-(3-Benzyloxy-benzyl)-pyrimidine-2,4,6-trione::CHEMBL37519

SMILES: Oc1[nH]c(=O)[nH]c(=O)c1Cc1cccc(OCc2ccccc2)c1

InChI Key: InChIKey=ICPFTYQMVNZYTI-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50078082   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Uridine phosphorylase 1 (Homo sapiens (Human))	BDBM50078082 (5-(3-Benzyloxy-benzyl)-pyrimidine-2,4,6-trione | C...) Show SMILES Oc1[nH]c(=O)[nH]c(=O)c1Cc1cccc(OCc2ccccc2)c1 Show InChI InChI=1S/C18H16N2O4/c21-16-15(17(22)20-18(23)19-16)10-13-7-4-8-14(9-13)24-11-12-5-2-1-3-6-12/h1-9H,10-11H2,(H3,19,20,21,22,23)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Parasitología y Biomedicina López-Neyra Curated by ChEMBL					Assay Description Inhibition of human uridine phosphorylase				Eur J Med Chem 45: 5140-9 (2010) Article DOI: 10.1016/j.ejmech.2010.08.026 BindingDB Entry DOI: 10.7270/Q24J0FB7
					More data for this Ligand-Target Pair
Purine Nucleoside Phosphorylase (PNP) (Plasmodium falciparum)	BDBM50078082 (5-(3-Benzyloxy-benzyl)-pyrimidine-2,4,6-trione | C...) Show SMILES Oc1[nH]c(=O)[nH]c(=O)c1Cc1cccc(OCc2ccccc2)c1 Show InChI InChI=1S/C18H16N2O4/c21-16-15(17(22)20-18(23)19-16)10-13-7-4-8-14(9-13)24-11-12-5-2-1-3-6-12/h1-9H,10-11H2,(H3,19,20,21,22,23)	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Parasitología y Biomedicina López-Neyra Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum PNP expressed in Escherichia coli BL21(DE3) cells by spectrophotometry				Eur J Med Chem 45: 5140-9 (2010) Article DOI: 10.1016/j.ejmech.2010.08.026 BindingDB Entry DOI: 10.7270/Q24J0FB7
					More data for this Ligand-Target Pair