Found 4 hits for monomerid = 50078117 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Golgi alpha-mannosidase II
(Drosophila melanogaster (Fruit fly)) | BDBM50078117
((1R,2R,3R,4S,5R)-4-AMINO-5-(METHYLTHIO)CYCLOPENTAN...)Show SMILES CS[C@@H]1[C@@H](N)[C@@H](O)[C@@H](O)[C@H]1O Show InChI InChI=1S/C6H13NO3S/c1-11-6-2(7)3(8)4(9)5(6)10/h2-6,8-10H,7H2,1H3/t2-,3+,4+,5+,6+/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL MMDB PC cid PC sid PDB UniChem
Similars
| MMDB PDB Article PubMed
| 36 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Toronto
| Assay Description The rate of hydrolysis catalyzed by drosophila golgi alpha-mannosidase II (dGMII)and in the presence of different concentration of inhibitor was meas... |
Chembiochem 10: 268-77 (2009)
Article DOI: 10.1002/cbic.200800538 BindingDB Entry DOI: 10.7270/Q2DZ06T7 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Golgi alpha-mannosidase II
(Homo sapiens (Human)) | BDBM50078117
((1R,2R,3R,4S,5R)-4-AMINO-5-(METHYLTHIO)CYCLOPENTAN...)Show SMILES CS[C@@H]1[C@@H](N)[C@@H](O)[C@@H](O)[C@H]1O Show InChI InChI=1S/C6H13NO3S/c1-11-6-2(7)3(8)4(9)5(6)10/h2-6,8-10H,7H2,1H3/t2-,3+,4+,5+,6+/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL MMDB PC cid PC sid PDB UniChem
Similars
| Article PubMed
| 90 | -9.99 | n/a | n/a | n/a | n/a | n/a | 5.6 | 37 |
University of Georgia
| |
Chembiochem 5: 1220-7 (2004)
Article DOI: 10.1002/cbic.200300842 BindingDB Entry DOI: 10.7270/Q2ZW1JF3 |
More data for this Ligand-Target Pair | |
Golgi alpha-mannosidase II
(Homo sapiens (Human)) | BDBM50078117
((1R,2R,3R,4S,5R)-4-AMINO-5-(METHYLTHIO)CYCLOPENTAN...)Show SMILES CS[C@@H]1[C@@H](N)[C@@H](O)[C@@H](O)[C@H]1O Show InChI InChI=1S/C6H13NO3S/c1-11-6-2(7)3(8)4(9)5(6)10/h2-6,8-10H,7H2,1H3/t2-,3+,4+,5+,6+/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL MMDB PC cid PC sid PDB UniChem
Similars
| Article PubMed
| 210 | -9.47 | n/a | n/a | n/a | n/a | n/a | 5.6 | 37 |
University of Georgia
| |
Chembiochem 5: 1220-7 (2004)
Article DOI: 10.1002/cbic.200300842 BindingDB Entry DOI: 10.7270/Q2ZW1JF3 |
More data for this Ligand-Target Pair | |
Mannosyl-oligosaccharide alpha-1,2-mannosidase isoform B
(Drosophila melanogaster) | BDBM50078117
((1R,2R,3R,4S,5R)-4-AMINO-5-(METHYLTHIO)CYCLOPENTAN...)Show SMILES CS[C@@H]1[C@@H](N)[C@@H](O)[C@@H](O)[C@H]1O Show InChI InChI=1S/C6H13NO3S/c1-11-6-2(7)3(8)4(9)5(6)10/h2-6,8-10H,7H2,1H3/t2-,3+,4+,5+,6+/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL MMDB PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a | n/a |
Slovak Academy of Sciences
Curated by ChEMBL
| Assay Description Inhibition of Drosophila melanogaster GM2b by spectrophotometry |
Eur J Med Chem 46: 944-52 (2011)
Article DOI: 10.1016/j.ejmech.2011.01.012 BindingDB Entry DOI: 10.7270/Q2MS3TQM |
More data for this Ligand-Target Pair | |