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BDBM50078224 7-Benzoyl-2-(2,6-dichloro-phenyl)-5-(2-methoxy-phenyl)-5H-thiazolo[3,2-a]pyrimidine-6-carboxylic acid 2-dimethylamino-ethyl ester::CHEMBL41630

SMILES: COc1ccccc1C1N2C=C(SC2=NC(C(=O)c2ccccc2)=C1C(=O)OCCN(C)C)c1c(Cl)cccc1Cl

InChI Key: InChIKey=NGXHQBDFQRAXJY-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50078224   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Metabotropic glutamate receptor 2


(Rattus norvegicus)		BDBM50078224
PNG
(7-Benzoyl-2-(2,6-dichloro-phenyl)-5-(2-methoxy-phe...)
Show SMILES COc1ccccc1C1N2C=C(SC2=NC(C(=O)c2ccccc2)=C1C(=O)OCCN(C)C)c1c(Cl)cccc1Cl |c:11,15,26|
Show InChI InChI=1S/C31H27Cl2N3O4S/c1-35(2)16-17-40-30(38)26-27(29(37)19-10-5-4-6-11-19)34-31-36(28(26)20-12-7-8-15-23(20)39-3)18-24(41-31)25-21(32)13-9-14-22(25)33/h4-15,18,28H,16-17H2,1-3H3
PDB

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



F. Hoffmann-La Roche Ltd.

Curated by ChEMBL


Assay Description
Inhibition of 1S,3R-ACPD (10 microM) -stimulated GTP gamma 35S binding on rat Metabotropic glutamate receptor 2 transfected in CHO cells

Bioorg Med Chem Lett 9: 1573-6 (1999)


BindingDB Entry DOI: 10.7270/Q2XS5TKC
More data for this
Ligand-Target Pair