BDBM50078232 2-(2,6-Dichloro-phenyl)-7-isopropyl-5-(2-methoxy-phenyl)-5H-thiazolo[3,2-a]pyrimidine-6-carboxylic acid 2-dimethylamino-ethyl ester::CHEMBL289388

SMILES: COc1ccccc1C1N2C=C(SC2=NC(C(C)C)=C1C(=O)OCCN(C)C)c1c(Cl)cccc1Cl

InChI Key: InChIKey=UZAQLUSKGDVMCF-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50078232   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 2 (Rattus norvegicus)	BDBM50078232 (2-(2,6-Dichloro-phenyl)-7-isopropyl-5-(2-methoxy-p...) Show SMILES COc1ccccc1C1N2C=C(SC2=NC(C(C)C)=C1C(=O)OCCN(C)C)c1c(Cl)cccc1Cl |c:11,15,20| Show InChI InChI=1S/C27H29Cl2N3O3S/c1-16(2)24-23(26(33)35-14-13-31(3)4)25(17-9-6-7-12-20(17)34-5)32-15-21(36-27(32)30-24)22-18(28)10-8-11-19(22)29/h6-12,15-16,25H,13-14H2,1-5H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Inhibition of 1S,3R-ACPD (10 microM) -stimulated GTP gamma 35S binding on rat Metabotropic glutamate receptor 2 transfected in CHO cells				Bioorg Med Chem Lett 9: 1573-6 (1999) BindingDB Entry DOI: 10.7270/Q2XS5TKC
					More data for this Ligand-Target Pair