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SMILES: CCCN(CC1CC1)c1nc(C)nc(Nc2c(OC)cc(OC)cc2OC)n1

InChI Key: InChIKey=QJUPTGZVGBXQDS-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50078345   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Corticotropin-releasing factor receptor 1


(Homo sapiens (Human))		BDBM50078345
PNG
(CHEMBL309789 | N-Cyclopropylmethyl-6-methyl-N-prop...)
Show SMILES CCCN(CC1CC1)c1nc(C)nc(Nc2c(OC)cc(OC)cc2OC)n1
Show InChI InChI=1S/C20H29N5O3/c1-6-9-25(12-14-7-8-14)20-22-13(2)21-19(24-20)23-18-16(27-4)10-15(26-3)11-17(18)28-5/h10-11,14H,6-9,12H2,1-5H3,(H,21,22,23,24)
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Article
PubMed
 8.00E+3n/an/an/an/an/an/an/an/a



The University of Wollongong

Curated by ChEMBL


Assay Description
Inhibition of [125I]-CRH binding to human Corticotropin releasing factor receptor 1.

J Med Chem 42: 2351-7 (1999)


Article DOI: 10.1021/jm9900117
BindingDB Entry DOI: 10.7270/Q2WS8SF0
More data for this
Ligand-Target Pair