BDBM50078391 (S)-1-[(R)-3-((2S,3R)-3-Amino-2-hydroxy-4-phenyl-butyryl)-thiazolidine-4-carbonyl]-pyrrolidine-2-carboxylic acid ((S)-1-carbamoyl-ethyl)-amide::CHEMBL79092

SMILES: C[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CSCN1C(=O)[C@@H](O)[C@H](N)Cc1ccccc1)C(N)=O

InChI Key: InChIKey=VXQMBLUFKRQEEZ-ITWBUVANSA-N

Data: 6 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50078391   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Membrane-bound aminopeptidase P (APP2) (Homo sapiens (Human))	BDBM50078391 ((S)-1-[(R)-3-((2S,3R)-3-Amino-2-hydroxy-4-phenyl-b...) Show SMILES C[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CSCN1C(=O)[C@@H](O)[C@H](N)Cc1ccccc1)C(N)=O Show InChI InChI=1S/C22H31N5O5S/c1-13(19(24)29)25-20(30)16-8-5-9-26(16)21(31)17-11-33-12-27(17)22(32)18(28)15(23)10-14-6-3-2-4-7-14/h2-4,6-7,13,15-18,28H,5,8-12,23H2,1H3,(H2,24,29)(H,25,30)/t13-,15+,16-,17-,18-/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia and Upjohn Curated by ChEMBL					Assay Description Inhibition against membrane bound human aminopeptidase P				J Med Chem 42: 2394-402 (1999) Article DOI: 10.1021/jm9805642 BindingDB Entry DOI: 10.7270/Q2N878ZS
					More data for this Ligand-Target Pair
Xaa-Pro dipeptidase (Homo sapiens (Human))	BDBM50078391 ((S)-1-[(R)-3-((2S,3R)-3-Amino-2-hydroxy-4-phenyl-b...) Show SMILES C[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CSCN1C(=O)[C@@H](O)[C@H](N)Cc1ccccc1)C(N)=O Show InChI InChI=1S/C22H31N5O5S/c1-13(19(24)29)25-20(30)16-8-5-9-26(16)21(31)17-11-33-12-27(17)22(32)18(28)15(23)10-14-6-3-2-4-7-14/h2-4,6-7,13,15-18,28H,5,8-12,23H2,1H3,(H2,24,29)(H,25,30)/t13-,15+,16-,17-,18-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia and Upjohn Curated by ChEMBL					Assay Description Inhibition against Prolidase from pig kidney.				J Med Chem 42: 2394-402 (1999) Article DOI: 10.1021/jm9805642 BindingDB Entry DOI: 10.7270/Q2N878ZS
					More data for this Ligand-Target Pair
Membrane-bound aminopeptidase P (APP2) (Homo sapiens (Human))	BDBM50078391 ((S)-1-[(R)-3-((2S,3R)-3-Amino-2-hydroxy-4-phenyl-b...) Show SMILES C[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CSCN1C(=O)[C@@H](O)[C@H](N)Cc1ccccc1)C(N)=O Show InChI InChI=1S/C22H31N5O5S/c1-13(19(24)29)25-20(30)16-8-5-9-26(16)21(31)17-11-33-12-27(17)22(32)18(28)15(23)10-14-6-3-2-4-7-14/h2-4,6-7,13,15-18,28H,5,8-12,23H2,1H3,(H2,24,29)(H,25,30)/t13-,15+,16-,17-,18-/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia and Upjohn Curated by ChEMBL					Assay Description Inhibition against membrane bound monkey aminopeptidase P				J Med Chem 42: 2394-402 (1999) Article DOI: 10.1021/jm9805642 BindingDB Entry DOI: 10.7270/Q2N878ZS
					More data for this Ligand-Target Pair
Xaa-Pro aminopeptidase 2 (Rattus norvegicus)	BDBM50078391 ((S)-1-[(R)-3-((2S,3R)-3-Amino-2-hydroxy-4-phenyl-b...) Show SMILES C[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CSCN1C(=O)[C@@H](O)[C@H](N)Cc1ccccc1)C(N)=O Show InChI InChI=1S/C22H31N5O5S/c1-13(19(24)29)25-20(30)16-8-5-9-26(16)21(31)17-11-33-12-27(17)22(32)18(28)15(23)10-14-6-3-2-4-7-14/h2-4,6-7,13,15-18,28H,5,8-12,23H2,1H3,(H2,24,29)(H,25,30)/t13-,15+,16-,17-,18-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia and Upjohn Curated by ChEMBL					Assay Description Activity against membrane bound rat aminopeptidase P				J Med Chem 42: 2394-402 (1999) Article DOI: 10.1021/jm9805642 BindingDB Entry DOI: 10.7270/Q2N878ZS
					More data for this Ligand-Target Pair
Xaa-Pro aminopeptidase 1 (Homo sapiens (Human))	BDBM50078391 ((S)-1-[(R)-3-((2S,3R)-3-Amino-2-hydroxy-4-phenyl-b...) Show SMILES C[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CSCN1C(=O)[C@@H](O)[C@H](N)Cc1ccccc1)C(N)=O Show InChI InChI=1S/C22H31N5O5S/c1-13(19(24)29)25-20(30)16-8-5-9-26(16)21(31)17-11-33-12-27(17)22(32)18(28)15(23)10-14-6-3-2-4-7-14/h2-4,6-7,13,15-18,28H,5,8-12,23H2,1H3,(H2,24,29)(H,25,30)/t13-,15+,16-,17-,18-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia and Upjohn Curated by ChEMBL					Assay Description Inhibition against cytosolic Aminopeptidase P from human heart.				J Med Chem 42: 2394-402 (1999) Article DOI: 10.1021/jm9805642 BindingDB Entry DOI: 10.7270/Q2N878ZS
					More data for this Ligand-Target Pair
Leucine aminopeptidase (Homo sapiens (Human))	BDBM50078391 ((S)-1-[(R)-3-((2S,3R)-3-Amino-2-hydroxy-4-phenyl-b...) Show SMILES C[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CSCN1C(=O)[C@@H](O)[C@H](N)Cc1ccccc1)C(N)=O Show InChI InChI=1S/C22H31N5O5S/c1-13(19(24)29)25-20(30)16-8-5-9-26(16)21(31)17-11-33-12-27(17)22(32)18(28)15(23)10-14-6-3-2-4-7-14/h2-4,6-7,13,15-18,28H,5,8-12,23H2,1H3,(H2,24,29)(H,25,30)/t13-,15+,16-,17-,18-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia and Upjohn Curated by ChEMBL					Assay Description Inhibition against Leucyl aminopeptidase from pig kidney.				J Med Chem 42: 2394-402 (1999) Article DOI: 10.1021/jm9805642 BindingDB Entry DOI: 10.7270/Q2N878ZS
					More data for this Ligand-Target Pair