BDBM50078392 (S)-1-((2R,3R)-3-Amino-2-hydroxy-5-methyl-hexanoyl)-pyrrolidine-2-carboxylic acid ((S)-1-carbamoyl-ethyl)-amide::CHEMBL81423
SMILES: CC(C)C[C@@H](N)[C@@H](O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(N)=O
InChI Key: InChIKey=PDGQBIYMLALKTR-WHOHXGKFSA-N
Data: 7 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Xaa-Pro aminopeptidase 1 (Homo sapiens (Human)) | BDBM50078392 ((S)-1-((2R,3R)-3-Amino-2-hydroxy-5-methyl-hexanoyl...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.50E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmacia and Upjohn Curated by ChEMBL | Assay Description Inhibition against Aminopeptidase P from human platelets. | J Med Chem 42: 2394-402 (1999) Article DOI: 10.1021/jm9805642 BindingDB Entry DOI: 10.7270/Q2N878ZS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Xaa-Pro aminopeptidase 1 (Homo sapiens (Human)) | BDBM50078392 ((S)-1-((2R,3R)-3-Amino-2-hydroxy-5-methyl-hexanoyl...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.50E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmacia and Upjohn Curated by ChEMBL | Assay Description Inhibition against cytosolic Aminopeptidase P from human heart. | J Med Chem 42: 2394-402 (1999) Article DOI: 10.1021/jm9805642 BindingDB Entry DOI: 10.7270/Q2N878ZS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Membrane-bound aminopeptidase P (APP2) (Homo sapiens (Human)) | BDBM50078392 ((S)-1-((2R,3R)-3-Amino-2-hydroxy-5-methyl-hexanoyl...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmacia and Upjohn Curated by ChEMBL | Assay Description Inhibition against membrane bound human aminopeptidase P | J Med Chem 42: 2394-402 (1999) Article DOI: 10.1021/jm9805642 BindingDB Entry DOI: 10.7270/Q2N878ZS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Membrane-bound aminopeptidase P (APP2) (Homo sapiens (Human)) | BDBM50078392 ((S)-1-((2R,3R)-3-Amino-2-hydroxy-5-methyl-hexanoyl...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmacia and Upjohn Curated by ChEMBL | Assay Description Inhibition against membrane bound monkey aminopeptidase P | J Med Chem 42: 2394-402 (1999) Article DOI: 10.1021/jm9805642 BindingDB Entry DOI: 10.7270/Q2N878ZS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Xaa-Pro aminopeptidase 2 (Rattus norvegicus) | BDBM50078392 ((S)-1-((2R,3R)-3-Amino-2-hydroxy-5-methyl-hexanoyl...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmacia and Upjohn Curated by ChEMBL | Assay Description Activity against membrane bound rat aminopeptidase P | J Med Chem 42: 2394-402 (1999) Article DOI: 10.1021/jm9805642 BindingDB Entry DOI: 10.7270/Q2N878ZS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Xaa-Pro dipeptidase (Homo sapiens (Human)) | BDBM50078392 ((S)-1-((2R,3R)-3-Amino-2-hydroxy-5-methyl-hexanoyl...) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.10E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmacia and Upjohn Curated by ChEMBL | Assay Description Inhibition against Prolidase from pig kidney. | J Med Chem 42: 2394-402 (1999) Article DOI: 10.1021/jm9805642 BindingDB Entry DOI: 10.7270/Q2N878ZS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucine aminopeptidase (Homo sapiens (Human)) | BDBM50078392 ((S)-1-((2R,3R)-3-Amino-2-hydroxy-5-methyl-hexanoyl...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmacia and Upjohn Curated by ChEMBL | Assay Description Inhibition against Leucyl aminopeptidase from pig kidney. | J Med Chem 42: 2394-402 (1999) Article DOI: 10.1021/jm9805642 BindingDB Entry DOI: 10.7270/Q2N878ZS | |||||||||||
More data for this Ligand-Target Pair |