BDBM50078723 (S)-2-[(4-tert-Butyl-benzyl)-methyl-amino]-4-methyl-pentanoic acid [(S)-2-(4-benzyloxy-phenyl)-1-tert-butylcarbamoyl-ethyl]-amide::CHEMBL299749
SMILES: CC(C)C[C@H](N(C)Cc1ccc(cc1)C(C)(C)C)C(=O)N[C@@H](Cc1ccc(OCc2ccccc2)cc1)C(=O)NC(C)(C)C
InChI Key: InChIKey=GCDHMGROXQUFNR-HEVIKAOCSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Voltage-gated calcium channel subunit alpha Cav2.2 (Homo sapiens (Human)) | BDBM50078723 ((S)-2-[(4-tert-Butyl-benzyl)-methyl-amino]-4-methy...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | PDB PubMed | n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company Curated by ChEMBL | Assay Description In vitro antagonism of N-type voltage sensitive calcium channel in IMR-32 assay using fluorescent [Ca2+] indicator Indo-11 in the presence of 5 micro... | Bioorg Med Chem Lett 9: 1813-8 (1999) BindingDB Entry DOI: 10.7270/Q2KD1X3X | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |