BDBM50078762 CHEMBL3416121

SMILES: [H][C@@]12C[C@H](O)CC[C@@]1([H])C(C)(C)Oc1cc(cc(O)c21)[C@@]12CC3CC(C[C@](C3)(C1)NC(=O)OC)C2

InChI Key: InChIKey=RMRPPULJEONUHI-KCRMERNJSA-N

Data: 3 KI  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50078762   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 2 (MOUSE)	BDBM50078762 (CHEMBL3416121) Show SMILES [H][C@@]12C[C@H](O)CC[C@@]1([H])C(C)(C)Oc1cc(cc(O)c21)[C@@]12CC3CC(C[C@](C3)(C1)NC(=O)OC)C2 |r,TLB:23:24:21.22.27:28,27:22:34:26.28.25,27:26:34:21.22.23,29:26:34:21.22.23| Show InChI InChI=1S/C27H37NO5/c1-25(2)20-5-4-18(29)9-19(20)23-21(30)7-17(8-22(23)33-25)26-10-15-6-16(11-26)13-27(12-15,14-26)28-24(31)32-3/h7-8,15-16,18-20,29-30H,4-6,9-14H2,1-3H3,(H,28,31)/t15?,16?,18-,19-,20-,26-,27-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Hawaii at Manoa Curated by ChEMBL					Assay Description Displacement of [3H]CP-55,940 from mouse CB2 receptor expressed in HEK293 cell membranes				J Med Chem 58: 3104-16 (2015) Article DOI: 10.1021/jm501960u BindingDB Entry DOI: 10.7270/Q22R3TBC
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50078762 (CHEMBL3416121) Show SMILES [H][C@@]12C[C@H](O)CC[C@@]1([H])C(C)(C)Oc1cc(cc(O)c21)[C@@]12CC3CC(C[C@](C3)(C1)NC(=O)OC)C2 |r,TLB:23:24:21.22.27:28,27:22:34:26.28.25,27:26:34:21.22.23,29:26:34:21.22.23| Show InChI InChI=1S/C27H37NO5/c1-25(2)20-5-4-18(29)9-19(20)23-21(30)7-17(8-22(23)33-25)26-10-15-6-16(11-26)13-27(12-15,14-26)28-24(31)32-3/h7-8,15-16,18-20,29-30H,4-6,9-14H2,1-3H3,(H,28,31)/t15?,16?,18-,19-,20-,26-,27-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Hawaii at Manoa Curated by ChEMBL					Assay Description Displacement of [3H]CP-55,940 from human CB2 receptor expressed in HEK293 cell membranes				J Med Chem 58: 3104-16 (2015) Article DOI: 10.1021/jm501960u BindingDB Entry DOI: 10.7270/Q22R3TBC
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Rattus norvegicus (rat))	BDBM50078762 (CHEMBL3416121) Show SMILES [H][C@@]12C[C@H](O)CC[C@@]1([H])C(C)(C)Oc1cc(cc(O)c21)[C@@]12CC3CC(C[C@](C3)(C1)NC(=O)OC)C2 |r,TLB:23:24:21.22.27:28,27:22:34:26.28.25,27:26:34:21.22.23,29:26:34:21.22.23| Show InChI InChI=1S/C27H37NO5/c1-25(2)20-5-4-18(29)9-19(20)23-21(30)7-17(8-22(23)33-25)26-10-15-6-16(11-26)13-27(12-15,14-26)28-24(31)32-3/h7-8,15-16,18-20,29-30H,4-6,9-14H2,1-3H3,(H,28,31)/t15?,16?,18-,19-,20-,26-,27-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	29	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Hawaii at Manoa Curated by ChEMBL					Assay Description Displacement of [3H]CP-55,940 from CB1 receptor in rat brain membranes				J Med Chem 58: 3104-16 (2015) Article DOI: 10.1021/jm501960u BindingDB Entry DOI: 10.7270/Q22R3TBC
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Rattus norvegicus (rat))	BDBM50078762 (CHEMBL3416121) Show SMILES [H][C@@]12C[C@H](O)CC[C@@]1([H])C(C)(C)Oc1cc(cc(O)c21)[C@@]12CC3CC(C[C@](C3)(C1)NC(=O)OC)C2 |r,TLB:23:24:21.22.27:28,27:22:34:26.28.25,27:26:34:21.22.23,29:26:34:21.22.23| Show InChI InChI=1S/C27H37NO5/c1-25(2)20-5-4-18(29)9-19(20)23-21(30)7-17(8-22(23)33-25)26-10-15-6-16(11-26)13-27(12-15,14-26)28-24(31)32-3/h7-8,15-16,18-20,29-30H,4-6,9-14H2,1-3H3,(H,28,31)/t15?,16?,18-,19-,20-,26-,27-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.60	n/a	n/a	n/a	n/a
University of Hawaii at Manoa Curated by ChEMBL					Assay Description Agonist activity at rat CB1 receptor expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP accumulation incubated for 60 mins				J Med Chem 58: 3104-16 (2015) Article DOI: 10.1021/jm501960u BindingDB Entry DOI: 10.7270/Q22R3TBC
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50078762 (CHEMBL3416121) Show SMILES [H][C@@]12C[C@H](O)CC[C@@]1([H])C(C)(C)Oc1cc(cc(O)c21)[C@@]12CC3CC(C[C@](C3)(C1)NC(=O)OC)C2 |r,TLB:23:24:21.22.27:28,27:22:34:26.28.25,27:26:34:21.22.23,29:26:34:21.22.23| Show InChI InChI=1S/C27H37NO5/c1-25(2)20-5-4-18(29)9-19(20)23-21(30)7-17(8-22(23)33-25)26-10-15-6-16(11-26)13-27(12-15,14-26)28-24(31)32-3/h7-8,15-16,18-20,29-30H,4-6,9-14H2,1-3H3,(H,28,31)/t15?,16?,18-,19-,20-,26-,27-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	16	n/a	n/a	n/a	n/a
University of Hawaii at Manoa Curated by ChEMBL					Assay Description Inverse agonist activity at human CB2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP accumulation incubated for ...				J Med Chem 58: 3104-16 (2015) Article DOI: 10.1021/jm501960u BindingDB Entry DOI: 10.7270/Q22R3TBC
					More data for this Ligand-Target Pair