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SMILES: CC(C)NC(=O)Nc1cccc(CN2c3ccccc3CCC(NC(=O)Nc3ccc4scnc4c3)C2=O)c1

InChI Key: InChIKey=WJYXHILWLVWUQD-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50079017   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neuropeptide Y receptor type 1


(Homo sapiens (Human))		BDBM50079017
PNG
(1-Benzothiazol-5-yl-3-{1-[3-(3-isopropyl-ureido)-b...)
Show SMILES CC(C)NC(=O)Nc1cccc(CN2c3ccccc3CCC(NC(=O)Nc3ccc4scnc4c3)C2=O)c1
Show InChI InChI=1S/C29H30N6O3S/c1-18(2)31-28(37)32-21-8-5-6-19(14-21)16-35-25-9-4-3-7-20(25)10-12-23(27(35)36)34-29(38)33-22-11-13-26-24(15-22)30-17-39-26/h3-9,11,13-15,17-18,23H,10,12,16H2,1-2H3,(H2,31,32,37)(H2,33,34,38)
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Article
PubMed
 24n/an/an/an/an/an/an/an/a



Shionogi & Company, Ltd.

Curated by ChEMBL


Assay Description
In vitro binding affinity towards Neuropeptide Y receptor type 1 was determined as potency to displace [125I]-peptide YY binding to human neuroblasto...

J Med Chem 42: 2621-32 (1999)


Article DOI: 10.1021/jm990044m
BindingDB Entry DOI: 10.7270/Q2XK8DRQ
More data for this
Ligand-Target Pair