Found 7 hits for monomerid = 50079022 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Farnesyl diphosphate synthase
(Homo sapiens (Human)) | BDBM50079022
(HP2O7(3-) | diphosphate | diphosphate(3-) | hydrog...)Show InChI InChI=1S/H4O7P2/c1-8(2,3)7-9(4,5)6/h(H2,1,2,3)(H2,4,5,6)/p-3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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MCE KEGG PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| 2.98E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford
Curated by ChEMBL
| Assay Description Inhibition of human recombinant FPPS expressed in Escherichia coli BL21 after 10 mins |
J Med Chem 51: 2187-95 (2008)
Article DOI: 10.1021/jm7015733 BindingDB Entry DOI: 10.7270/Q2W95B18 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Farnesyl diphosphate synthase
(Homo sapiens (Human)) | BDBM50079022
(HP2O7(3-) | diphosphate | diphosphate(3-) | hydrog...)Show InChI InChI=1S/H4O7P2/c1-8(2,3)7-9(4,5)6/h(H2,1,2,3)(H2,4,5,6)/p-3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
MCE KEGG PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| 4.05E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford
Curated by ChEMBL
| Assay Description Inhibition of human recombinant FPPS expressed in Escherichia coli BL21 |
J Med Chem 51: 2187-95 (2008)
Article DOI: 10.1021/jm7015733 BindingDB Entry DOI: 10.7270/Q2W95B18 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Ornithine carbamoyltransferase
(Homo sapiens (Human)) | BDBM50079022
(HP2O7(3-) | diphosphate | diphosphate(3-) | hydrog...)Show InChI InChI=1S/H4O7P2/c1-8(2,3)7-9(4,5)6/h(H2,1,2,3)(H2,4,5,6)/p-3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
MCE KEGG PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| 2.40E+5 | n/a | n/a | n/a | n/a | n/a | n/a | 6.0 | n/a |
Universit£tstrasse 16
Curated by ChEMBL
| Assay Description Binding affinity against ornithine transcarbamoylase (OTC) produced by Streptococcus faecalis The buffer taken for this study is 50 mM maleate, 0.5 m... |
J Med Chem 42: 2633-40 (1999)
Article DOI: 10.1021/jm991008q BindingDB Entry DOI: 10.7270/Q2NV9JX8 |
More data for this Ligand-Target Pair | |
Ornithine carbamoyltransferase
(Homo sapiens (Human)) | BDBM50079022
(HP2O7(3-) | diphosphate | diphosphate(3-) | hydrog...)Show InChI InChI=1S/H4O7P2/c1-8(2,3)7-9(4,5)6/h(H2,1,2,3)(H2,4,5,6)/p-3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
MCE KEGG PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| 8.90E+5 | n/a | n/a | n/a | n/a | n/a | n/a | 7.0 | n/a |
Universit£tstrasse 16
Curated by ChEMBL
| Assay Description Binding affinity against ornithine transcarbamoylase (OTC) produced by Streptococcus faecalis The buffer taken for this study is 50 mM Tris.HCl, 0.5 ... |
J Med Chem 42: 2633-40 (1999)
Article DOI: 10.1021/jm991008q BindingDB Entry DOI: 10.7270/Q2NV9JX8 |
More data for this Ligand-Target Pair | |
Ornithine carbamoyltransferase
(Homo sapiens (Human)) | BDBM50079022
(HP2O7(3-) | diphosphate | diphosphate(3-) | hydrog...)Show InChI InChI=1S/H4O7P2/c1-8(2,3)7-9(4,5)6/h(H2,1,2,3)(H2,4,5,6)/p-3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
MCE KEGG PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| 2.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a | 8.0 | n/a |
Universit£tstrasse 16
Curated by ChEMBL
| Assay Description Binding affinity against ornithine transcarbamoylase (OTC) produced by Streptococcus faecalis The buffer taken for this study is 50 mM Tris.HCl, 0.5 ... |
J Med Chem 42: 2633-40 (1999)
Article DOI: 10.1021/jm991008q BindingDB Entry DOI: 10.7270/Q2NV9JX8 |
More data for this Ligand-Target Pair | |
Farnesyl diphosphate synthase
(Homo sapiens (Human)) | BDBM50079022
(HP2O7(3-) | diphosphate | diphosphate(3-) | hydrog...)Show InChI InChI=1S/H4O7P2/c1-8(2,3)7-9(4,5)6/h(H2,1,2,3)(H2,4,5,6)/p-3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
MCE KEGG PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| n/a | n/a | 2.43E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford
Curated by ChEMBL
| Assay Description Inhibition of human recombinant FPPS expressed in Escherichia coli BL21 |
J Med Chem 51: 2187-95 (2008)
Article DOI: 10.1021/jm7015733 BindingDB Entry DOI: 10.7270/Q2W95B18 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Farnesyl diphosphate synthase
(Homo sapiens (Human)) | BDBM50079022
(HP2O7(3-) | diphosphate | diphosphate(3-) | hydrog...)Show InChI InChI=1S/H4O7P2/c1-8(2,3)7-9(4,5)6/h(H2,1,2,3)(H2,4,5,6)/p-3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
MCE KEGG PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| n/a | n/a | 1.81E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford
Curated by ChEMBL
| Assay Description Inhibition of human recombinant FPPS expressed in Escherichia coli BL21 after 10 mins |
J Med Chem 51: 2187-95 (2008)
Article DOI: 10.1021/jm7015733 BindingDB Entry DOI: 10.7270/Q2W95B18 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |