BDBM50079404 CHEMBL3417206

SMILES: COC(=O)c1sc2ncnc(Nc3ccc(=O)n(C)c3)c2c1C

InChI Key: InChIKey=MODNPTORBFXJNS-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50079404   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MAP kinase-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human))	BDBM50079404 (CHEMBL3417206) Show SMILES COC(=O)c1sc2ncnc(Nc3ccc(=O)n(C)c3)c2c1C Show InChI InChI=1S/C15H14N4O3S/c1-8-11-13(18-9-4-5-10(20)19(2)6-9)16-7-17-14(11)23-12(8)15(21)22-3/h4-7H,1-3H3,(H,16,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of South Australia Curated by ChEMBL					Assay Description Inhibition of Mnk1 (unknown origin) pre-incubated for 10 mins before eIF4E peptide substrate addition by ADP-Glo kinase assay				Eur J Med Chem 95: 116-26 (2015) Article DOI: 10.1016/j.ejmech.2015.03.032 BindingDB Entry DOI: 10.7270/Q28917K3
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM50079404 (CHEMBL3417206) Show SMILES COC(=O)c1sc2ncnc(Nc3ccc(=O)n(C)c3)c2c1C Show InChI InChI=1S/C15H14N4O3S/c1-8-11-13(18-9-4-5-10(20)19(2)6-9)16-7-17-14(11)23-12(8)15(21)22-3/h4-7H,1-3H3,(H,16,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of South Australia Curated by ChEMBL					Assay Description Inhibition of Mnk2 (unknown origin) pre-incubated for 10 mins before eIF4E peptide substrate addition by ADP-Glo kinase assay				Eur J Med Chem 95: 116-26 (2015) Article DOI: 10.1016/j.ejmech.2015.03.032 BindingDB Entry DOI: 10.7270/Q28917K3
					More data for this Ligand-Target Pair